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  1. Many transcription factors are involved in the formation of the brain during the development of Drosophila melanogaster. The transcription factor Earmuff (Erm), a member of the forebrain embryonic zinc finger fam...

    Authors: Kirsten Hildebrandt, Sabrina Kübel, Marie Minet, Nora Fürst, Christine Klöppel, Eva Steinmetz and Uwe Walldorf
    Citation: Hereditas 2021 158:41
    Content type: Research Published on:

  2. Autosomal dominant osteopetrosis type II (ADO2) is a genetically and phenotypically metabolic bone disease, caused by osteoclast abnormalities. The pathways dysregulated in ADO2 could lead to the defects in os...

    Authors: Chunhong Li, Yu Shangguan, Peng Zhu, Weier Dai, Donge Tang, Minglin Ou and Yong Dai
    Citation: Hereditas 2021 158:40
    Content type: Research Published on:

  3. Oral lichen planus (OLP) is a T cell-mediated autoimmune disease recognized as an oral potential malignant disorder (OPMD) with the precise mechanism unknown. This study focused on the transcriptional profiles...

    Authors: Haoyu Wang, Yiwen Deng, Siqi Peng, Li Yan, Hui Xu, Qingzhong Wang and Zhengyu Shen
    Citation: Hereditas 2021 158:39
    Content type: Research Published on:

  4. Alterations in genes encoding chromatin regulatory proteins are prevalent in cancers and may confer oncogenic properties and molecular changes linked to therapy resistance. However, the impact of copy number a...

    Authors: Zhiwei Xing, Buhuan Ma, Weiting Sun, Yimin Sun and Caixia Liu
    Citation: Hereditas 2021 158:38
    Content type: Research Published on:

  5. Osteoarthritis (OA) and rheumatoid arthritis (RA) were two major joint diseases with similar clinical phenotypes. This study aimed to determine the mechanistic similarities and differences between OA and RA by...

    Authors: Yanzhi Ge, Zuxiang Chen, Yanbin Fu, Xiujuan Xiao, Haipeng Xu, Letian Shan, Peijian Tong and Li Zhou
    Citation: Hereditas 2021 158:37
    Content type: Research Published on:

  12. The formation of the Bicoid (Bcd) gradient in the early Drosophila is one of the most fascinating observations in biology and serves as a paradigm for gradient formation, yet its mechanism is still not fully unde...

    Authors: Xiaoli Cai, Inge Rondeel and Stefan Baumgartner
    Citation: Hereditas 2021 158:29
    Content type: Research Published on:

  13. The life cycle of Taenia solium is characterized by different stages of development, requiring various kinds of hosts that can appropriately harbor the eggs (proglottids), the oncospheres, the larvae and the adul...

    Authors: Xinrui Wang, Weiyi Song, Guanyu Ji, Yining Song, Xiaolei Liu, Xuenong Luo, Mingyuan Liu and Shumin Sun
    Citation: Hereditas 2021 158:28
    Content type: Research Published on:

  14. FBXW7 gene expression is positively correlated with glycolipid metabolism and is associated with diabetes in animal models. In the current study, we focused on exploring whether genetic variants of the FBXW7 g...

    Authors: Shi-Qi Yan, Dilare Adi, Cheng Liu, Meng-Meng Wang, Jialin Abuzhalihana, Yun Wu, Zhen-Yan Fu, Yi-Ning Yang, Xiao-Mei Li, Xiang Xie, Fen Liu, Bang-Dang Chen and Yi-Tong Ma
    Citation: Hereditas 2021 158:27
    Content type: Research Published on:

  15. miRNAs are a type of conserved, small RNA molecule that regulate gene expression and play an important role in the growth and development of plants. miRNAs are involved in seed germination, root development, s...

    Authors: Hao Qu, Yue Liu, Huibing Jiang, Yufei Liu, Weixi Song and Linbo Chen
    Citation: Hereditas 2021 158:26
    Content type: Research Published on:

  16. Alzheimer’s disease (AD) is a fatal neurodegenerative disorder, and the lesions originate in the entorhinal cortex (EC) and hippocampus (HIP) at the early stage of AD progression. Gaining insight into the mole...

    Authors: Haoming Li, Linqing Zou, Jinhong Shi and Xiao Han
    Citation: Hereditas 2021 158:25
    Content type: Research Published on:

  20. Psoriasis is a complex chronic inflammatory skin disease. The aim of this study was to analyze potential risk genes and molecular mechanisms associated with psoriasis.

    Authors: Huilin Wang, Wenjun Chen, Jin He, Wenjuan Xu and Jiangwei Liu
    Citation: Hereditas 2021 158:21
    Content type: Research Published on:

  21. Craniosynostosis, defined as premature fusion of one or more cranial sutures, affects approximately 1 in every 2000–2500 live births. Sagittal craniosynostosis (CS), the most prevalent form of isolated cranios...

    Authors: Jin Xu, Qing Yan, Chengcheng Song, Jingjia Liang, Liang Zhao, Xin Zhang, Zhenkun Weng, Cheng Xu, Qian Liu, Shuqin Xu, Lu Pang, Liye Zhang, Yuan Sun, Gang Wang and Aihua Gu
    Citation: Hereditas 2021 158:20
    Content type: Research Published on:

  23. CLOVES syndrome (OMIM# 612918) is a rare overgrowth disorder resulted from mosaic gain-of-function mutations in the PIK3CA gene. All the reported CLOVES-associated PIK3CA mutations are missense mutations affectin...

    Authors: Wei Yan, Bin Zhang, Huijun Wang, Ran Mo, Xingyuan Jiang, Wen Qin, Lin Ma and Zhimiao Lin
    Citation: Hereditas 2021 158:18
    Content type: Research Published on:

  25. CCN1 plays a crucial role in the modulation of cardiovascular diseases. However, whether CCN1 genetic variants are involved in the susceptibility of ACS remains unknown. Hence, the present study investigates the ...

    Authors: Yan-Hong Li, Jun-Yi Luo, Bin-Bin Fang, Guo-Li Du, Ting Tian, Fen Liu, Xiao-Mei Li and Yi-Ning Yang
    Citation: Hereditas 2021 158:16
    Content type: Research Published on:

  26. Oral squamous cell carcinoma (OSCC) is a malignant cancer, the survival rate of patients is disappointing. Therefore, it is necessary to identify the driven-genes and prognostic biomarkers in OSCC.

    Authors: Wanli Yang, Wei Zhou, Xinhui Zhao, Xiaoqian Wang, Lili Duan, Yiding Li, Liaoran Niu, Junfeng Chen, Yujie Zhang, Yu Han, Daiming Fan and Liu Hong
    Citation: Hereditas 2021 158:15
    Content type: Research Published on:

  28. Sepsis and septic shock are life-threatening diseases with high mortality rate in intensive care unit (ICU). Acute kidney injury (AKI) is a common complication of sepsis, and its occurrence is a poor prognosti...

    Authors: Yun Tang, Xiaobo Yang, Huaqing Shu, Yuan Yu, Shangwen Pan, Jiqian Xu and You Shang
    Citation: Hereditas 2021 158:13
    Content type: Research Published on:

  29. Coronary artery disease (CAD) is the leading cause of death worldwide. In this study, we aimed to explore whether some genetic variants of the human IDOL gene were associated with CAD among Chinese population ...

    Authors: Dilare Adi, Jialin Abuzhalihan, Jing Tao, Yun Wu, Ying-Hong Wang, Fen Liu, Yi-Ning Yang, Xiang Ma, Xiao-Mei Li, Xiang Xie, Zhen-Yan Fu and Yi-Tong Ma
    Citation: Hereditas 2021 158:12
    Content type: Research Published on:

    The Correction to this article has been published in Hereditas 2021 158:19

  30. CSL transcription factors are central to signal transduction in the highly conserved Notch signaling pathway. CSL acts as a molecular switch: depending on the cofactors recruited, CSL induces either activation...

    Authors: Dorina B. Wolf, Dieter Maier and Anja C. Nagel
    Citation: Hereditas 2021 158:11
    Content type: Brief report Published on:

  32. Osteosarcoma is the primary bone malignant neoplasm that often develops metastasis. Increasing evidences have shown that non-coding RNAs (ncRNAs) relate to the progression of osteosarcoma. However, the ncRNAs’...

    Authors: Yucheng Fu, Qi Liu, Qiyuan Bao, Junxiang Wen, Zhuochao Liu, Yuehao Hu, Guoyu He, Cheng Peng, Yiqi Xu and Weibin Zhang
    Citation: Hereditas 2021 158:9
    Content type: Research Published on:

  34. The Aedes aegypti mosquito is a threat to human health across the globe. The A. aegypti genome was recently re-sequenced and re-assembled. Due to a combination of long-read PacBio and Hi-C sequencing, the AaegL5 ...

    Authors: Ronald J. Nowling, Susanta K. Behura, Marc S. Halfon, Scott J. Emrich and Molly Duman-Scheel
    Citation: Hereditas 2021 158:7
    Content type: Brief report Published on:

  36. The disability rate associated with rheumatoid arthritis (RA) ranks high among inflammatory joint diseases. However, the cause and potential molecular events are as yet not clear. Here, we aimed to identify di...

    Authors: Yanzhi Ge, Li Zhou, Zuxiang Chen, Yingying Mao, Ting Li, Peijian Tong and Letian Shan
    Citation: Hereditas 2021 158:5
    Content type: Research Published on:

  38. Preterm infants are a special population that vulnerable to respiratory syncytial virus (RSV) infection and the lower respiratory tract infections (LRTIs) caused by RSV could be severe and even life-threating....

    Authors: Junyan Gao, Xueping Zhu, Mingfu Wu, Lijun Jiang, Fudong Wang and Shan He
    Citation: Hereditas 2021 158:3
    Content type: Research Published on:

  40. Immunotherapy, especially anti-PD-1, is becoming a pillar of modern muscle-invasive bladder cancer (MIBC) treatment. However, the objective response rates (ORR) are relatively low due to the lack of precise bi...

    Authors: Zihao Chen, Guojun Liu, Guoqing Liu, Mikhail A. Bolkov, Khyber Shinwari, Irina A. Tuzankina, Valery A. Chereshnev and Zhifeng Wang
    Citation: Hereditas 2021 158:1
    Content type: Research Published on:

  42. The Mendelian Society of Lund launched Hereditas in 1920. The purpose of this article is to give an overview of Hereditas’s hundred-year existence, focusing on the conditions for a learned society to publish a sc...

    Authors: Anna Tunlid, Ulf Kristoffersson and Fredrik Åström
    Citation: Hereditas 2020 157:50
    Content type: Research Published on:

    The Correction to this article has been published in Hereditas 2021 158:8

  43. East Asia constitutes one-fifth of the global population and exhibits substantial genetic diversity. However, genetic investigations on populations in this region have been largely under-represented compared w...

    Authors: Ziqing Pan and Shuhua Xu
    Citation: Hereditas 2020 157:49
    Content type: Review Published on:

  44. The founders of Hereditas envisioned that race biology would be a major subject that had social applications with utmost importance in the near future. Anthropometrics was in this context understood to be the ...

    Authors: Anssi Saura
    Citation: Hereditas 2020 157:48
    Content type: Review Published on:

  45. Mutations in HARS2 are one of the genetic causes of Perrault syndrome, characterized by sensorineural hearing loss (SNHL) and ovarian dysfunction. Here, we identified two novel putative pathogenic variants of HAR...

    Authors: Jing Yu, Wei Jiang, Li Cao, Xiaoxue Na and Jiyun Yang
    Citation: Hereditas 2020 157:47
    Content type: Brief report Published on:

  47. This is the Editorial for a series of articles illuminating the history and success story of Hereditas, one of the oldest journals in the area of genetics. For this reason, we invite you to read this special s...

    Authors: Yongyong Shi and Stefan Baumgartner
    Citation: Hereditas 2020 157:45
    Content type: Editorial Published on:

  49. The Reelin (RELN) gene encodes the protein reelin, which is a large extracellular matrix glycoprotein that plays a key role in brain development. Additionally, this protein may be involved in memory formation, ne...

    Authors: Jiajun Yin, Yana Lu, Shui Yu, Zhanzhan Dai, Fuquan Zhang and Jianmin Yuan
    Citation: Hereditas 2020 157:43
    Content type: Research Published on:
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