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  1. Alzheimer’s disease (AD) is a fatal neurodegenerative disorder, and the lesions originate in the entorhinal cortex (EC) and hippocampus (HIP) at the early stage of AD progression. Gaining insight into the mole...

    Authors: Haoming Li, Linqing Zou, Jinhong Shi and Xiao Han
    Citation: Hereditas 2021 158:25
    Content type: Research Published on:

  5. Psoriasis is a complex chronic inflammatory skin disease. The aim of this study was to analyze potential risk genes and molecular mechanisms associated with psoriasis.

    Authors: Huilin Wang, Wenjun Chen, Jin He, Wenjuan Xu and Jiangwei Liu
    Citation: Hereditas 2021 158:21
    Content type: Research Published on:

  6. Craniosynostosis, defined as premature fusion of one or more cranial sutures, affects approximately 1 in every 2000–2500 live births. Sagittal craniosynostosis (CS), the most prevalent form of isolated cranios...

    Authors: Jin Xu, Qing Yan, Chengcheng Song, Jingjia Liang, Liang Zhao, Xin Zhang, Zhenkun Weng, Cheng Xu, Qian Liu, Shuqin Xu, Lu Pang, Liye Zhang, Yuan Sun, Gang Wang and Aihua Gu
    Citation: Hereditas 2021 158:20
    Content type: Research Published on:

  8. CLOVES syndrome (OMIM# 612918) is a rare overgrowth disorder resulted from mosaic gain-of-function mutations in the PIK3CA gene. All the reported CLOVES-associated PIK3CA mutations are missense mutations affectin...

    Authors: Wei Yan, Bin Zhang, Huijun Wang, Ran Mo, Xingyuan Jiang, Wen Qin, Lin Ma and Zhimiao Lin
    Citation: Hereditas 2021 158:18
    Content type: Research Published on:

  10. CCN1 plays a crucial role in the modulation of cardiovascular diseases. However, whether CCN1 genetic variants are involved in the susceptibility of ACS remains unknown. Hence, the present study investigates the ...

    Authors: Yan-Hong Li, Jun-Yi Luo, Bin-Bin Fang, Guo-Li Du, Ting Tian, Fen Liu, Xiao-Mei Li and Yi-Ning Yang
    Citation: Hereditas 2021 158:16
    Content type: Research Published on:

  11. Oral squamous cell carcinoma (OSCC) is a malignant cancer, the survival rate of patients is disappointing. Therefore, it is necessary to identify the driven-genes and prognostic biomarkers in OSCC.

    Authors: Wanli Yang, Wei Zhou, Xinhui Zhao, Xiaoqian Wang, Lili Duan, Yiding Li, Liaoran Niu, Junfeng Chen, Yujie Zhang, Yu Han, Daiming Fan and Liu Hong
    Citation: Hereditas 2021 158:15
    Content type: Research Published on:

  13. Sepsis and septic shock are life-threatening diseases with high mortality rate in intensive care unit (ICU). Acute kidney injury (AKI) is a common complication of sepsis, and its occurrence is a poor prognosti...

    Authors: Yun Tang, Xiaobo Yang, Huaqing Shu, Yuan Yu, Shangwen Pan, Jiqian Xu and You Shang
    Citation: Hereditas 2021 158:13
    Content type: Research Published on:

  14. Coronary artery disease (CAD) is the leading cause of death worldwide. In this study, we aimed to explore whether some genetic variants of the human IDOL gene were associated with CAD among Chinese population ...

    Authors: Dilare Adi, Jialin Abuzhalihan, Jing Tao, Yun Wu, Ying-Hong Wang, Fen Liu, Yi-Ning Yang, Xiang Ma, Xiao-Mei Li, Xiang Xie, Zhen-Yan Fu and Yi-Tong Ma
    Citation: Hereditas 2021 158:12
    Content type: Research Published on:

    The Correction to this article has been published in Hereditas 2021 158:19

  15. CSL transcription factors are central to signal transduction in the highly conserved Notch signaling pathway. CSL acts as a molecular switch: depending on the cofactors recruited, CSL induces either activation...

    Authors: Dorina B. Wolf, Dieter Maier and Anja C. Nagel
    Citation: Hereditas 2021 158:11
    Content type: Brief report Published on:

  17. Osteosarcoma is the primary bone malignant neoplasm that often develops metastasis. Increasing evidences have shown that non-coding RNAs (ncRNAs) relate to the progression of osteosarcoma. However, the ncRNAs’...

    Authors: Yucheng Fu, Qi Liu, Qiyuan Bao, Junxiang Wen, Zhuochao Liu, Yuehao Hu, Guoyu He, Cheng Peng, Yiqi Xu and Weibin Zhang
    Citation: Hereditas 2021 158:9
    Content type: Research Published on:

  19. The Aedes aegypti mosquito is a threat to human health across the globe. The A. aegypti genome was recently re-sequenced and re-assembled. Due to a combination of long-read PacBio and Hi-C sequencing, the AaegL5 ...

    Authors: Ronald J. Nowling, Susanta K. Behura, Marc S. Halfon, Scott J. Emrich and Molly Duman-Scheel
    Citation: Hereditas 2021 158:7
    Content type: Brief report Published on:

  21. The disability rate associated with rheumatoid arthritis (RA) ranks high among inflammatory joint diseases. However, the cause and potential molecular events are as yet not clear. Here, we aimed to identify di...

    Authors: Yanzhi Ge, Li Zhou, Zuxiang Chen, Yingying Mao, Ting Li, Peijian Tong and Letian Shan
    Citation: Hereditas 2021 158:5
    Content type: Research Published on:

  23. Preterm infants are a special population that vulnerable to respiratory syncytial virus (RSV) infection and the lower respiratory tract infections (LRTIs) caused by RSV could be severe and even life-threating....

    Authors: Junyan Gao, Xueping Zhu, Mingfu Wu, Lijun Jiang, Fudong Wang and Shan He
    Citation: Hereditas 2021 158:3
    Content type: Research Published on:

  25. Immunotherapy, especially anti-PD-1, is becoming a pillar of modern muscle-invasive bladder cancer (MIBC) treatment. However, the objective response rates (ORR) are relatively low due to the lack of precise bi...

    Authors: Zihao Chen, Guojun Liu, Guoqing Liu, Mikhail A. Bolkov, Khyber Shinwari, Irina A. Tuzankina, Valery A. Chereshnev and Zhifeng Wang
    Citation: Hereditas 2021 158:1
    Content type: Research Published on:

  27. The Mendelian Society of Lund launched Hereditas in 1920. The purpose of this article is to give an overview of Hereditas’s hundred-year existence, focusing on the conditions for a learned society to publish a sc...

    Authors: Anna Tunlid, Ulf Kristoffersson and Fredrik Åström
    Citation: Hereditas 2020 157:50
    Content type: Research Published on:

    The Correction to this article has been published in Hereditas 2021 158:8

  28. East Asia constitutes one-fifth of the global population and exhibits substantial genetic diversity. However, genetic investigations on populations in this region have been largely under-represented compared w...

    Authors: Ziqing Pan and Shuhua Xu
    Citation: Hereditas 2020 157:49
    Content type: Review Published on:

  29. The founders of Hereditas envisioned that race biology would be a major subject that had social applications with utmost importance in the near future. Anthropometrics was in this context understood to be the ...

    Authors: Anssi Saura
    Citation: Hereditas 2020 157:48
    Content type: Review Published on:

  30. Mutations in HARS2 are one of the genetic causes of Perrault syndrome, characterized by sensorineural hearing loss (SNHL) and ovarian dysfunction. Here, we identified two novel putative pathogenic variants of HAR...

    Authors: Jing Yu, Wei Jiang, Li Cao, Xiaoxue Na and Jiyun Yang
    Citation: Hereditas 2020 157:47
    Content type: Brief report Published on:

  32. This is the Editorial for a series of articles illuminating the history and success story of Hereditas, one of the oldest journals in the area of genetics. For this reason, we invite you to read this special s...

    Authors: Yongyong Shi and Stefan Baumgartner
    Citation: Hereditas 2020 157:45
    Content type: Editorial Published on:

  34. The Reelin (RELN) gene encodes the protein reelin, which is a large extracellular matrix glycoprotein that plays a key role in brain development. Additionally, this protein may be involved in memory formation, ne...

    Authors: Jiajun Yin, Yana Lu, Shui Yu, Zhanzhan Dai, Fuquan Zhang and Jianmin Yuan
    Citation: Hereditas 2020 157:43
    Content type: Research Published on:

  36. Cervical cancer (CC) is the third most common gynecological malignancy around the world. Cisplatin is an effective drug, but cisplatin resistance is a vital factor limiting the clinical usage of cisplatin. Enh...

    Authors: Xiaoling Wu, Youwen Zhong, Qing Chen, Xin Zhang and Hua Zhang
    Citation: Hereditas 2020 157:41
    Content type: Research Published on:

  37. Avocado is an important cash crop in Tanzania, however its genetic diversity is not thoroughly investigated. This study was undertaken to explore the genetic diversity of avocado in the southern highlands usin...

    Authors: Ibrahim Juma, Mulatu Geleta, Agnes Nyomora, Ganapathi Varma Saripella, Helena Persson Hovmalm, Anders S. Carlsson, Moneim Fatih and Rodomiro Ortiz
    Citation: Hereditas 2020 157:40
    Content type: Research Published on:

  38. The growth process of the tea plant (Camellia sinensis) includes vegetative growth and reproductive growth. The reproductive growth period is relatively long (approximately 1.5 years), during which a large number...

    Authors: Yufei Liu, Dandan Pang, Yiping Tian, Youyong Li, Huibing Jiang, Yunnan Sun, Lifei Xia and Linbo Chen
    Citation: Hereditas 2020 157:39
    Content type: Research Published on:

  41. Protein phosphatase 2A (PP2A) is a serine/threonine phosphatase that serves as a key regulator of cellular physiology in the context of apoptosis, mitosis, and DNA damage responses. Canonically, PP2A functions...

    Authors: Xiao Lei, Na Ma, Lehui Du, Yanjie Liang, Pei Zhang, Yanan Han and Baolin Qu
    Citation: Hereditas 2020 157:36
    Content type: Review Published on:

  42. Congenital melanocytic nevus (CMN) represent a benign proliferative skin disease in the epidermis and dermis. CMN are historically known to be associated with activating NRAS or BRAF mutations. Melanoma freque...

    Authors: Yun Zou, Yi Sun, Xiaojing Zeng, Yun Liu, Qingqing Cen, Hao Gu, Xiaoxi Lin, Ren Cai and Hui Chen
    Citation: Hereditas 2020 157:35
    Content type: Brief report Published on:

  45. Non-small cell lung cancer (NSCLC) is the major type of lung cancer with high morbidity and poor prognosis. Erlotinib, an inhibitor of epidermal growth factor receptor (EGFR), has been clinically applied for N...

    Authors: Huyue Zhou, Qiumei Xiang, Changpeng Hu, Jing Zhang, Qian Zhang and Rong Zhang
    Citation: Hereditas 2020 157:32
    Content type: Research Published on:

  46. Genetic diathesis of suicide is supported by family and twin studies. Few candidate gene pathways are known, but does not explain fully the complexity of suicide genetic risk. Recent investigations opting for ...

    Authors: Gaurav Gupta, Ravi Deval, Anshuman Mishra, Shashank Upadhyay, Piyoosh Kumar Singh and V. R. Rao
    Citation: Hereditas 2020 157:31
    Content type: Brief report Published on:

  47. The aim of this study was to identify the candidate biomarkers and pathways associated with psoriasis. GSE13355 and GSE14905 were extracted from the Gene Expression Omnibus (GEO) database. Then the differentia...

    Authors: Yongqi Luo, Yangyang Luo, Jing Chang, Zhenghui Xiao and Bin Zhou
    Citation: Hereditas 2020 157:30
    Content type: Research Published on:
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Hereditas

ISSN: 1601-5223

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