Hereditas

The evolution of transcriptional repressors in the Notch signaling pathway: a computational analysis

The Notch signaling pathway is highly conserved in eukaryotes. Notch repressors, however, are only known from arthropods and vertebrates (Drosophila: Hairless, vertebrates: SHARP/MINT and KyoT2). Database searches revealed homologues of Hairless only after the Chelicerata-Mandibulata radiation, SHARP only in vertebrates, and KyoT2 with a ΦWΦP interacting motif only in placental mammals. However, the data provide a hypothesis on the evolution of KyoT2 from Prickle-like ancestors. These Prickle-like ancestors contain a novel, putative CSL interacting motif. If it were confirmed by experiments, this work has uncovered a novel, very ancestral CSL interactor found in the entire animal kingdom.

Aims and scope

For almost a century, Hereditas has published original cutting-edge research and reviews. As the Official journal of the Mendelian Society of Lund, the journal welcomes research from across all areas of genetics and genomics. Topics of interest include human and medical genetics, animal and plant genetics, microbial genetics, agriculture and bioinformatics. Articles covering novel viral sequences or the use of new technology and software in genomic research are also welcomed.

Content type: Research
| 26 April 2019

Identification of the defense-related gene VdWRKY53 from the wild grapevine Vitis davidii using RNA sequencing and ectopic expression analysis in Arabidopsis

Authors: Ying Zhang, Jia-Long Yao, Hu Feng, Jianfu Jiang, Xiucai Fan, Yun-Fei Jia, Ran Wang and Chonghuai Liu
Content type: Research
| 25 April 2019

First report of bicolour FISH of Berberis diaphana and B. soulieana reveals interspecific differences and co-localization of (AGGGTTT)₃ and rDNA 5S in B. diaphana

Authors: Juncheng Liu and Xiaomei Luo
Content type: Research
| 18 April 2019

Transcriptome profiling of the fertile parent and sterile hybrid in tea plant flower buds

Authors: Linbo Chen, Hao Qu, Lifei Xia, Yue Liu, Huibing Jiang, Yunnan Sun, Mingzhi Liang and Changjun Jiang
Content type: Research
| 9 April 2019

The inhibition of miR-126 in cell migration and invasion of cervical cancer through regulating ZEB1

Authors: Jiqin Xu, Hongyun Wang, Huiyan Wang, Qing Chen, Li Zhang, Chao Song, Qianqian Zhou and Ying Hong
Content type: Research
| 6 February 2019

Global transcriptome analysis of H5N1 influenza virus-infected human cells

Authors: Ying Cao, Kun Zhang, Lirong Liu, Wei Li, Bin Zhu, Shuang Zhang, Ping Xu, Wenjun Liu and Jing Li

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Content type: Review
| 15 June 2017

Adaptation of human skin color in various populations

Authors: Lian Deng and Shuhua Xu
Content type: Research
| 6 April 2018

Genetic structure, divergence and admixture of Han Chinese, Japanese and Korean populations

Authors: Yuchen Wang, Dongsheng Lu, Yeun-Jun Chung and Shuhua Xu
Content type: Research
| 22 October 2015

Analysis of genetic diversity of Tunisian caprifig (Ficus carica L.) accessions using simple sequence repeat (SSR) markers

Authors: Awatef Essid, Fateh Aljane, Ali Ferchichi and Jose Ignacio Hormaza
Content type: Research
| 19 April 2016

Genetic variation, population structure and linkage disequilibrium in Switchgrass with ISSR, SCoT and EST-SSR markers

Authors: Yu Zhang, Haidong Yan, Xiaomei Jiang, Xiaoli Wang, Linkai Huang, Bin Xu, Xinquan Zhang and Lexin Zhang
Content type: Research
| 26 January 2017

PCR-based assays for validation of single nucleotide polymorphism markers in rice and mungbean

Authors: Thu Giang Thi Bui, Nguyen Thi Lan Hoa, Jo-yi Yen and Roland Schafleitner

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Previous content

Hereditas launched with BioMed Central in 2015, transferring from its previous publisher Wiley. All back content is available in the archive.

Editors-in-Chief

Stefan Baumgartner, Lund University
Yongyong Shi, Shanghai Jiao Tong University

Society information

The Mendelian Society of Lund was founded in 1910 and except for a short break during 1912-1916 has been active ever since. In 1920, the Society started to publish Hereditas, a scientific journal in genetics. In the post-genomic era, the scope of Hereditas has evolved to include any research on genomic analysis.

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05 June 2018

Hereditas

The evolution of transcriptional repressors in the Notch signaling pathway: a computational analysis

Aims and scope

Articles

Identification of the defense-related gene VdWRKY53 from the wild grapevine Vitis davidii using RNA sequencing and ectopic expression analysis in Arabidopsis

First report of bicolour FISH of Berberis diaphana and B. soulieana reveals interspecific differences and co-localization of (AGGGTTT)₃ and rDNA 5S in B. diaphana

Transcriptome profiling of the fertile parent and sterile hybrid in tea plant flower buds

The inhibition of miR-126 in cell migration and invasion of cervical cancer through regulating ZEB1

Global transcriptome analysis of H5N1 influenza virus-infected human cells

Adaptation of human skin color in various populations

Genetic structure, divergence and admixture of Han Chinese, Japanese and Korean populations

Analysis of genetic diversity of Tunisian caprifig (Ficus carica L.) accessions using simple sequence repeat (SSR) markers

Genetic variation, population structure and linkage disequilibrium in Switchgrass with ISSR, SCoT and EST-SSR markers

PCR-based assays for validation of single nucleotide polymorphism markers in rice and mungbean

Previous content

Editors-in-Chief

Society information

Latest Tweets

From the blog

Q&A with Professor Kathryn Roeder

Breast Cancer Awareness Month: Highlighting Breast Cancer Research in Cell Biology and Genetics

How a salmon gets its spots

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