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Fig. 8 | Hereditas

Fig. 8

From: Comprehensive analysis revealed the immunoinflammatory targets of rheumatoid arthritis based on intestinal flora, miRNA, transcription factors, and RNA-binding proteins databases, GSEA and GSVA pathway observations, and immunoinfiltration typing

Fig. 8

Construction of correlation network and RNA-binding protein (RBP) correlation analysis based on differentially expressed genes targeted by RA (DERATGs). A Transcription factor (TF)-target network for DERATGs. The arrow is directed toward the targeted DERATGs from the predicted TF. B Micro RNA (miRNA)-mRNA network. Red nodes represent DERATGs, green nodes represent related miRNAs, and lines represent the regulatory relationships between DERATGs and miRNAs. C Heat map of the correlation between 54 DERATGs and RBP genes in the expression profile of the GSE55235 dataset. Positively correlated genes are represented by red, whereas negatively correlated genes are represented by blue. D Heat map of the correlation between 54 DERATGs and RBP genes in the expression profile of the GSE55457 dataset. Positively correlated genes are represented by red, whereas negatively correlated genes are represented by blue

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