Fig. 5

GO functional enrichment of the ACP-colon key targets. A Cellular component. GO:0005634, nucleus; GO:0005829, cytosol; GO:0005737, cytoplasm; GO:0005654, nucleoplasm; GO:0032991, macromolecular complex; GO:0005739, mitochondrion; GO:0016020, membrane; GO:0000785, chromatin; GO:0005576, extracellular region; GO:0005813, centrosome; GO:0048471, perinuclear region of cytoplasm. B Molecular function. GO:0005515, protein binding; GO:0042802, identical protein binding; GO:0019901, protein kinase binding; GO:0005524, ATP binding; GO:0019899, enzyme binding; GO:0003677, DNA binding; GO:0042803, protein homodimerization activity; GO:0004672, protein kinase activity; GO:0031625, ubiquitin protein ligase binding; GO:0004674, protein serine/threonine kinase activity. (C) Biological process. GO:0006468, protein phosphorylation; GO:0007165, signal transduction; GO:0042493, response to drug; GO:0043066, negative regulation of apoptotic process; GO:0000122, negative regulation of transcription from RNA polymerase II promoter; GO:0010629, negative regulation of gene expression; GO:0010628, positive regulation of gene expression; GO:0006915, apoptotic process; GO:0045944, positive regulation of transcription from RNA polymerase II promoter; GO:0009410, response to xenobiotic stimulus; GO:0051301, cell division; GO:0045893, positive regulation of transcription, DNA-templated; GO:0000086, G2/M transition of mitotic cell cycle; GO:0001934, positive regulation of protein phosphorylation; GO:0006974, cellular response to DNA damage stimulus; GO:0051726, regulation of cell cycle; GO:0071407, cellular response to organic cyclic compound