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Fig. 3 | Hereditas

Fig. 3

From: Mechanisms of Actinidia chinensis Planch in treating colon cancer based on the integration of network pharmacology, molecular docking, and experimental verification

Fig. 3

GO functional and KEGG pathway enrichment of ACP target genes (Count numbers ≥ 50). A GO enrichment of ACP targets. GO:0005829, cytosol; GO:0005737, cytoplasm; GO:0005886, plasma membrane; GO:0005634, nucleus; GO:0016021, integral component of membrane; GO:0005654, nucleoplasm; GO:0070062, extracellular exosome; GO:0016020, membrane; GO:0005576, extracellular region; GO:0005887, integral component of plasma membrane; GO:0005615, extracellular space; GO:0005739, mitochondrion; GO:0005783, endoplasmic reticulum; GO:0005789, endoplasmic reticulum membrane; GO:0000785, chromatin; GO:0005515, protein binding; GO:0042802, identical protein binding; GO:0005524, ATP binding; GO:0046872, metal ion binding; GO:0019899, enzyme binding; GO:0042803, protein homodimerization activity; GO:0008270, zinc ion binding; GO:0003677, DNA binding; GO:0007165, signal transduction; GO:0045944, positive regulation of transcription from RNA polymerase II promoter; GO:0045893, positive regulation of transcription, DNA-templated; GO:0008284, positive regulation of cell proliferation; GO:0006468, protein phosphorylation; GO:0042493, response to drug; GO:0010628, positive regulation of gene expression; GO:0043066, negative regulation of apoptotic process; GO:0000122, negative regulation of transcription from RNA polymerase II promoter. B KEGG pathway enrichment analysis of ACP targets. The dots represent the number of genes, and the shades of color represent the logarithm of the base 10 P value

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