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Fig. 6 | Hereditas

Fig. 6

From: Elevated HMGB1 promotes the malignant progression and contributes to cisplatin resistance of non-small cell lung cancer

Fig. 6

HMGB1 overexpression promoted the cisplatin resistance in vivo. (a) Representative IHC results of the expression levels of P-gp, Bax and BCL-2 after cisplatin and paclitaxel treatment. Scale bar, 100 μm. (b-c) Western blot was performed to detect the expression of LRP, MRP, P-gp, Caspase, Bax and Bcl-2. * P < 0.05, ** P < 0.01 and *** P < 0.001

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Hereditas

ISSN: 1601-5223

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