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Fig. 4 | Hereditas

Fig. 4

From: Elevated HMGB1 promotes the malignant progression and contributes to cisplatin resistance of non-small cell lung cancer

Fig. 4

HMGB1 promoted the migration, invasion and drug resistance of A549 cells and A549-DDP cells. (a) Transwell assay was conducted to determine the effects of HMGB1 on the migration ability of A549 cells and A549-DDP cells. Magnification, ×200. (b) Transwell assay was conducted to detect the effect of HMGB1 on the invasive ability of A549 cells and A549-DDP cells. Magnification, ×200. (c-d) Western blot was performed to detect the expression levels of LRP, MRP, P-gp, Caspase, Bax and Bcl-2 in A549 cells and A549-DDP cells under cisplatin and paclitaxel treatment, respectively. *P < 0.05, **P < 0.01 and ***P < 0.001

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ISSN: 1601-5223

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