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Fig. 1 | Hereditas

Fig. 1

From: Elevated HMGB1 promotes the malignant progression and contributes to cisplatin resistance of non-small cell lung cancer

Fig. 1

The HMGB1 (high mobility group box B-1) expression in pleural effusion and non-small cell lung cancer (NSCLC) samples. (a-d) The expression of proinflammatory factors, IL-1β, IL-6, IL-8, and HMGB1 in MPE vs. BPE by ELISA. (e-f) The mRNA and protein expression of HMGB1 in NSCLC were detected by qRT-PCR (e) and Western blot (f). (g) Western blot was performed to detect the expression of LRP, MRP, P-gp, Caspase, Bax and Bcl-2. (h-i) Immunohistochemical assay was performed to detect the expression of HMGB1, LRP, MRP, P-gp, Bax and Bcl-2 in NSCLC samples. Magnification, ×200. * P < 0.05, ** P < 0.01 and *** P < 0.001

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