Fig. 8From: Identifying and predicting the pathogenic effects of a novel variant inducing severe early onset MMA: a bioinformatics approachThe mutation range of the MMAB gene. Each specific color demonstrates a type of variant. The black, red, gray, blue, and green colors indicate missense/nonsense, splicing, small deletion, small duplication, and regulatory variants, respectively. As shown, the majority of variants are aggregated on exon 7, indicating the existence of a hot spot in this exonBack to article page