Fig. 6From: Identifying and predicting the pathogenic effects of a novel variant inducing severe early onset MMA: a bioinformatics approachThe heatmap representation of the functional effect for residues 155-210 of MMAB. The SNAP2 heatmap representation of the functional effect of amino acid substitutions for residues 155–210 of MMAB shows that substitution at position 186 to either W or Q strongly affects the protein functionBack to article page