Fig. 9
From: Circular RNA circHMCU promotes breast tumorigenesis through miR-4458/PGK1 regulatory cascade
PGK1 overexpression reversed the effects of miR-138-5p mimic on BC cell invasion and migration. MDA-MB-231 and MCF-7 cells were transfected with mimic NC, miR-4458 mimic, miR-4458 mimic + pcDNA, or miR-4458 mimic + pcDNA-PGK1. A Cell invasion was tested by transwell assay. B-D Migration was examined by wound-healing assay. E The levels of MMP9 and MMP2 proteins were estimated by western blot. *P < 0.05