Fig. 2

Clinical attributes and survival rates of COAD subtypes in clusters A–C. a Based on the similarity between the expression level of lncRNAs related to m6A regulators and proportion of fuzzy clustering measure, k = 3 was determined. b Principal component analysis was performed to further analyze the gene expression profile between the isomers,revealing differences among the three isomers. c Clinical correlation heatmap of clusters A–C and the clinical characteristics of the three subtypes were compared. The TNM staging ratio of cluster B was higher than that of gene clusters A and C (P < 0.01). Clusters A and C contained a lower proportion of patients with distant and lymph node metastases compared to that in cluster B (P < 0.05). d Kaplan–Meier curves for overall survival of patients with COAD in the 3 groups. The OS difference among lncRNA clusters of the three m6A methylation-related prognoses was significant. The OS rate in group B was significantly lower than that in the other two groups. *P < 0.05, **P < 0.01, ***P < 0.001. COAD, colon adenocarcinoma