Skip to main content
Fig. 3 | Hereditas

Fig. 3

From: Multiomics landscape of the autosomal dominant osteopetrosis type II disease-specific induced pluripotent stem cells

Fig. 3

m6A modification signatures of ADO2-iPSCs. (A). Boxplots of all genes. (B). Density map of all genes. (C). Clustered heat map of differentially expressed m6A-methylated genes (DEMGs) between ADO2-iPSCs and NC-iPSCs. (D). Volcano plot of the DEMGs. (E). The distribution of differential m6A peaks on gene functional elements. (F). Sequence logo showing the top motifs enriched across differential m6A peaks identified from ADO2-iPSCs and NC-iPSCs. (G). ISG15 m6A level in ADO2-iPSCs sample is higher than NC-iPSCs as shown in Figs. 4 by IGV software. (H). GO enrichment analysis of the DEMGs; (I). KEGG pathway enrichment analysis of the DEMGs

Back to article page

Hereditas

ISSN: 1601-5223

Contact us