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Table 4 Distribution of SNPs of IDOL gene in Uygur male subjects

From: Genetic polymorphism of IDOL gene was associated with the susceptibility of coronary artery disease in Han population in Xinjiang, China

Genotype

Model

 

Case (n, %)

Control (n, %)

P value

rs2072783

(A > G)

Codominant

AA

111 (49.0)

69 (49.6)

0.508

GA

113 (45.7)

61 (43.9)

 

GG

23 (9.3)

9 (6.5)

 

Dominant

AA

111 (49.0)

69 (49.6)

0.374

GA + GG

136 (55.1)

70 (50.4)

 

Recessive

AA + GA

224 (90.7)

130 (93.5)

0.332

GG

23 (9.3)

9 (6.5)

 

Additive

GG + AA

134 (54.3)

78 (56.1)

0.724

GA

113 (45.7)

61 (43.9)

 

A

335 (67.8)

199 (71.6)

0.276

G

159 (32.2)

79 (28.4)

 

rs2205796

(T > G)

Codominant

TT

144 (58.3)

83 (59.7)

0.602

GT

95 (38.5)

49 (35.3)

 

GG

8 (3.2)

7 (5.0)

 

Dominant

TT

144 (58.3)

83 (59.7)

0.787

GT + GG

103 (41.7)

56 (40.3)

 

Recessive

TT + GT

239 (96.8)

132 (95.0)

0.380

GG

8 (3.2)

7 (5.0)

 

Additive

GG + TT

152 (61.5)

90 (64.7)

0.531

GT

95 (38.5)

49 (35.3)

 

T

383 (77.5)

222 (77.9)

0.906

G

111 (22.5)

63 (22.1)

 

rs909562

(A > G)

Codominant

AA

123 (49.8)

74 (53.2)

0.755

GA

102 (41.3)

52 (37.4)

 

GG

22 (8.9)

13 (9.4)

 

Dominant

AA

123 (49.8)

74 (53.2)

0.516

GA + GG

124 (50.2)

65 (46.8)

 

Recessive

GA + AA

225 (91.1)

126 (90.6)

0.884

GG

22 (8.9)

13 (9.4)

 

Additive

GG + AA

145 (58.7)

87 (62.6)

0.454

GA

102 (41.3)

52 (37.4)

 

A

348 (70.4)

200 (71.9)

0.660

G

146 (29.6)

78 (28.1)

 
  1. Note: In the Uygur male participants, there were no significant differences in the distributions of genotypes and alleles, dominant model, recessive model, and additive model for three SNPs between case and control groups (all P > 0.05)