Table 3 Distribution of SNPs of IDOL gene in Han female subjects
Genotype | Model | Case (n, %) | Control (n, %) | P value | |
|---|---|---|---|---|---|
rs2072783 (A > G) | Codominant | AA | 42 (36.5) | 67 (37.6) | 0.283 |
GA | 60 (52.2) | 80 (44.9) | |||
GG | 13 (11.3) | 31 (17.4) | |||
Dominant | AA | 42 (36.5) | 67 (37.6) | 0.847 | |
GA + GG | 73 (63.5) | 111 (64.4) | |||
Recessive | AA + GA | 102 (87.7) | 147 (82.6) | 0.153 | |
GG | 13 (11.3) | 31 (17.4) | |||
Additive | GG + AA | 55 (47.8) | 98 (55.1) | 0.226 | |
GA | 60 (52.2) | 80 (44.9) | |||
A | 144 (62.6) | 214 (60.3) | 0.573 | ||
G | 86 (37.4) | 141 (39.7) | |||
rs2205796 (T > G) | Codominant | TT | 59 (51.3) | 117 (65.7) | 0.048 |
GT | 49 (42.6) | 54 (30.3) | |||
GG | 7 (6.1) | 7 (3.9) | |||
Dominant | TT | 59 (51.3) | 117 (65.7) | 0.014 | |
GT + GG | 56 (48.7) | 61 (34.3) | |||
Recessive | TT + GT | 108 (93.9) | 171 (96.1) | 0.399 | |
GG | 7 (6.1) | 7 (3.9) | |||
Additive | GG + TT | 66 (57.4) | 124 (69.7) | 0.032 | |
GT | 49 (42.6) | 54 (30.3) | |||
T | 167 (72.6) | 288 (80.9) | 0.019 | ||
G | 63 (27.4) | 68 (19.1) | |||
rs909562 (A > G) | Codominant | AA | 49 (42.6) | 59 (33.1) | 0.254 |
GA | 52 (45.2) | 92 (51.7) | |||
GG | 14 (12.2) | 27 (15.2) | |||
Dominant | AA | 49 (42.6) | 59 (33.1) | 0.101 | |
GA + GG | 66 (57.4) | 119 (66.9) | |||
Recessive | GA + AA | 101 (87.8) | 151 (84.8) | 0.471 | |
GG | 14 (12.2) | 27 (15.2) | |||
Additive | GG + AA | 63 (54.8) | 86 (48.3) | 0.280 | |
GA | 52 (45.2) | 92 (51.7) | |||
A | 150 (65.2) | 210 (59.0) | 0.130 | ||
G | 80 (34.8) | 146 (41.0) |