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Fig. 3 | Hereditas

Fig. 3

From: Defining muscle-invasive bladder cancer immunotypes by introducing tumor mutation burden, CD8+ T cells, and molecular subtypes

Fig. 3

Genetic, transcriptome, and epigenetic characterization of MIBC immunotypes. a-c Genetic alterations in immunotype a, b, and c. d Dendrogram generated using the WGCNA shows nine highly parsimonious modules e PCC matrix between MEs and clinical traits. Each row corresponds to a module eigengene, each column corresponds to a trait, and each cell consists of the corresponding correlation and P-value. Among them, the blue module was the most relevant to the MIBC immunotypes. f Bubble plots for both enriched 10 KEGG pathways and 15 GO terms, for the blue module. g The protein-protein interaction network for genes within the blue module, and the green nodes represent the eight hub genes we identified

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Hereditas

ISSN: 1601-5223

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