Table 2 KEGG pathway enrichment for the genes in the coexpression modules of HCM

Module black

hsa03010:Ribosome

48

15.68627

7.55E-42

hsa00190:Oxidative phosphorylation

22

7.189542

1.93E-11

hsa05010: Alzheimer’s disease

17

5.555556

6.60E-06

hsa05012: Parkinson’s disease

15

4.901961

1.72E-05

hsa04932: Non-alcoholic fatty liver disease (NAFLD)

15

4.901961

3.45E-05

Module blue

hsa04120: Ubiquitin mediated proteolysis

14

3.465347

1.61E-04

hsa03015: mRNA surveillance pathway

10

2.475248

0.001237

hsa00270: Cysteine and methionine metabolism

6

1.485149

0.004544

hsa04114: Oocyte meiosis

10

2.475248

0.004845

hsa01130: Biosynthesis of antibiotics

14

3.465347

0.008644

Module brown

hsa01200: Carbon metabolism

13

3.651685

4.17E-06

hsa00020: Citrate cycle (TCA cycle)

7

1.966292

3.22E-05

hsa04144: Endocytosis

15

4.213483

5.62E-04

hsa04141: Protein processing in endoplasmic reticulum

12

3.370787

8.83E-04

hsa01130: Biosynthesis of antibiotics

13

3.651685

0.001751

Module green

hsa00190: Oxidative phosphorylation

7

3.846154

0.001913

hsa05010: Alzheimer’s disease

7

3.846154

0.00608

hsa05016: Huntington’s disease

7

3.846154

0.011398

hsa05012: Parkinson’s disease

6

3.296703

0.012855

Module pink

hsa00020: Citrate cycle (TCA cycle)

3

3

0.015527

hsa01200: Carbon metabolism

4

4

0.035113

Module turquoise

hsa03010: Ribosome

31

3.703704

4.60E-11

hsa05016: Huntington’s disease

31

3.703704

2.27E-07

hsa03050: Proteasome

12

1.433692

2.10E-05

hsa05012: Parkinson’s disease

21

2.508961

1.12E-04

hsa00190: Oxidative phosphorylation

20

2.389486

1.37E-04

Module yellow

hsa04145: Phagosome

14

4.093567

5.39E-05

hsa04510: Focal adhesion

15

4.385965

3.75E-04

hsa04611: Platelet activation

11

3.216374

0.001026

hsa04974: Protein digestion and absorption

9

2.631579

0.00112

hsa05146: Amoebiasis

9

2.631579

0.003661