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Fig. 5 | Hereditas

Fig. 5

From: Enhancer of mRNA Decapping protein 4 (EDC4) interacts with replication protein a (RPA) and contributes to Cisplatin resistance in cervical Cancer by alleviating DNA damage

Fig. 5

RPA knockdown reversed the inhibitory effect of EDC4 on cisplatin-induced DNA damage. a The level of EDC4, RPA1 and RPA2 in cells with EDC4 overexpression (or RPA knockdown) analyzed by Western blot. b The cell growth of HeLa (with EDC4 overexpression with/or RPA knockdown) evaluated by colony formation assay. c The DNA damage of HeLa (with EDC4 knockdown) analyzed by γH2AX immunofluorescent staining. **p < 0.01 vs. Vector; ##p < 0.01 vs. EDC4 + siNC

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Hereditas

ISSN: 1601-5223

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