Association between polymorphisms in mannose-binding lectin 2 gene with pulmonary tuberculosis susceptibility

Shen, Wenhao; Xiao, Li; Li, Yang; Zhou, Daming; Zhang, Wei

doi:10.1186/s41065-020-00146-w

Hereditas

Table 1 Basic information of the association between 4 SNPs in MBL2 and TB, especially for PTB susceptibility

From: Association between polymorphisms in mannose-binding lectin 2 gene with pulmonary tuberculosis susceptibility

First author	Year	Origin	Ethnicity	Source of	Type	Case	Control	Case			Control				Method	NOS
Ref No				Control				MM	MW	WW	MM	MW	WW
rs7096206								XX/GG	XY/GC	YY/CC	XX/GG	XY/GC	YY/CC	HWE
Liu [10]	2006	China	Asian	PB	PTB	141	212	6	44	91	7	54	151	0.43	PCR-SSP/PCR-SSOP	7
Wu	2017	China	Asian	HB	PTB	151	453	7	47	97	15	120	318	0.379	PCR-RFLP/PCR-SSCP	6
Thye [41]	2011	Germany	Caucasian	PB	PTB	1859	2180	26	396	1437	31	486	1663	0.503	DASH-FRET	7
Feng [30]	2016	China	Asian	HB	PTB	99	89	0	9	90	1	26	62	0.336	Taqman	5
Liu	2015	China	Asian	HB	PTB	112	120	11	35	66	2	40	78	0.215	PCR-RFLP	7
Chen [24]	2014	China	Asian	PB	PTB	205	216	5	77	123	8	49	159	0.098	PCR-SSP	7
Wang [42]	2009	China	Asian	PB	PTB	449	249	12	122	315	7	61	181	0.503	AMLR	7
Alagarasu [19]	2007	India	Asian	HB	total	109	146	3	44	62	13	61	72	0.987	PCR-SSP	6
Chen [25]	2015	China	Asian	PB	total	503	419	12	166	325	10	113	296	0.839	PCR-SSP	8
Amiri [20]	2017	Iran	Asian	PB	PTB	100	100	5	36	59	7	29	64	0.159	PCR-SSP	7
Cruz [27]	2013	Brazil	Caucasian	HB	PTB	119	148	4	40	75	6	32	110	0.076	Sequencing	6
Cruz [27]	2013	Brazil	Caucasian	HB	EPTB	36	148	1	9	26	6	32	110	0.076	Sequencing	6
rs11003125								LL	LH	HH	LL	LH	HH	HWE
Liu [10]	2006	China	Asian	PB	PTB	141	212	31	66	44	58	105	49	0.911	PCR-SSP/PCR-SSOP	7
Thye [41]	2011	Germany	Caucasian	PB	PTB	1843	2174	7	265	1571	9	287	1878	0.577	DASH-FRET	7
Feng [30]	2016	China	Asian	HB	PTB	99	89	28	45	26	21	36	32	0.092	Taqman	5
Li [34]	2011	China	Asian	PB	PTB	231	226	34	92	105	31	106	89	0.949	PCR-SSP	7
Wu	2017	China	Asian	HB	PTB	151	453	41	64	46	104	248	101	0.043	PCR-RFLP/PCR-SSCP	6
Zhou [46]	2011	China	Asian	HB	PTB	226	141	58	101	67	42	10	89	< 0.01	PCR-SSP	6
Zhang [44]	2011	China	Asian	HB	PTB	220	213	29	75	116	51	76	86	< 0.01	PCR-SSP	6
Wang [42]	2009	China	Asian	PB	PTB	449	249	91	235	123	60	108	81	0.046	AMLR	7
Amiri [20]	2017	Iran	Asian	PB	PTB	100	100	22	43	35	30	48	22	0.735	PCR-SSP	7
Cruz [27]	2013	Brazil	Caucasian	HB	PTB	119	148	66	45	8	68	61	19	0.367	Sequencing	6
Cruz [27]	2013	Brazil	Caucasian	HB	EPTB	36	148	16	18	2	68	61	19	0.367	Sequencing	6
rs7095891								QQ	QP	PP	QQ	QP	PP	HWE
Liu [10]	2006	China	Asian	PB	PTB	141	212	1	22	118	2	39	171	0.891	PCR-SSP/PCR-SSOP	7
Wu	2017	China	Asian	HB	PTB	151	453	1	26	124	2	87	364	0.181	PCR-RFLP/PCR-SSCP	6
Thye [41]	2011	Germany	Caucasian	PB	PTB	1953	2230	308	920	725	319	1086	825	0.205	DASH-FRET	7
Zhou [46]	2011	China	Asian	HB	PTB	226	231	24	90	112	25	89	117	0.201	PCR-SSP	6
Feng [30]	2016	China	Asian	HB	PTB	99	89	7	34	58	0	24	65	0.141	Taqman	5
Wang [42]	2009	China	Asian	PB	PTB	449	249	3	114	332	2	64	183	0.155	AMLR	7
Zhang [44]	2011	China	Asian	HB	PTB	220	213	17	31	172	21	36	156	< 0.01	PCR-SSP	6
Amiri [20]	2017	Iran	Asian	PB	PTB	100	100	3	21	76	5	26	69	0.233	PCR-SSP	7
AA/AO/OO								OO	OA	AA	OO	OA	AA	HWE
Garcia-Laorden [17]	2006	Spain	Caucasian	HB	total	106	344	3	33	70	27	134	183	0.721	PCR-RFLP	6
Søborg	2003	Denmark	Caucasian	PB	total/ White	59	250	4	18	37	7	86	157	0.235	PCR-SSP	8
Søborg	2003	Denmark	Caucasian	PB	total/ Nonwhite	50	250	4	12	34	7	86	157	0.235	PCR-SSP	8
Capparelli [22]	2009	Italy	Caucasian	HB	PTB	274	288	61	158	55	10	112	166	0.087	Sequencing	6
Garcıa-Gasalla [32]	2014	Spain	Caucasian	HB	total	76	106	4	24	48	1	34	71	0.156	PCR-SSP	6
Alagarasu [19]	2007	India	Asian	HB	total	275	146	25	87	145	7	53	86	0.747	PCR-SSP	6
Zhao [45]	2014	China	Asian	PB	PTB	900	870	101	279	520	53	303	514	0.352	PCR-RFLP	7
Li [34]	2011	China	Asian	PB	PTB	231	226	3	57	171	3	37	186	0.461	PCR-SSP	7
Li [33]	2009	China	Asian	HB	PTB	141	152	6	56	79	8	38	106	0.075	PCR-SSP	6
Liu [10]	2006	China	Asian	PB	PTB	141	212	4	34	103	4	42	166	0.487	PCR-SSP/PCR-SSOP	7
Zhou [47]	2012	China	Asian	HB	PTB	226	231	14	106	106	5	80	146	0.114	PCR-SSP	6
Liu	2015	China	Asian	HB	PTB	112	120	3	29	80	2	22	96	0.576	PCR-RFLP	7
Fang [29]	2011	China	Asian	HB	PTB	100	100	1	25	74	0	25	75	0.153	PCR-RFLP	6
Wu	2017	China	Asian	HB	PTB	151	454	2	37	112	8	97	348	0.681	PCR-RFLP/PCR-SSCP	6
Singla	2011	India	Asian	HB	PTB	286	397	11	100	175	35	155	207	0.441	PCR-RFLP	6
Singla	2011	India	Asian	HB	EPTB	71	397	2	26	43	35	155	207	0.441	PCR-RFLP	6
Özbaþ-Gerçeker	2003	Turkey	Caucasian	PB	PTB	49	100	0	9	40	4	20	76	0.09	PCR	7
Wit [28]	2011	South Africa	African	PB	total	499	313	2	134	363	0	102	211	< 0.01	PCR-RFLP	8
Feng [30]	2016	China	Asian	HB	PTB	381	267	14	177	190	12	176	79	< 0.01	Taqman	5
Wang [42]	2009	China	Asian	PB	PTB	449	249	4	133	312	3	82	164	0.038	AMLR	7
Thye [41]	2011	Germany	Caucasian	PB	PTB	1893	1040	193	815	885	126	426	488	0.029	DASH-FRET	7
Ceylan [23]	2017	Turkey	Caucasian	HB	total	69	70	8	13	48	12	11	47	< 0.01	PCR-RFLP	7
Amiri [20]	2017	Iran	Asian	PB	PTB	100	100	2	29	69	1	27	72	0.374	PCR-SSP	7
Cruz [27]	2013	Brazil	Caucasian	HB	PTB	119	148	7	41	71	6	34	108	0.129	Sequencing	6
Cruz [27]	2013	Brazil	Caucasian	HB	EPTB	36	148	1	14	21	6	34	108	0.129	Sequencing	6
Selvaraj [37]	1999	India	Asian	PB	PTB	202	109	22	73	107	2	39	68	0.175	PCR-RFLP	7
Araújo	2013	Brazil	Caucasian	HB	PTB	133	159	2	47	84	2	56	101	0.058	PCR	6
Araújo	2013	Brazil	Caucasian	HB	EPTB	34	159	1	15	18	2	56	101	0.058	PCR	6
Fitness [31]	2004	UK	Caucasian	PB	total	322	546	12	105	205	24	160	362	0.245	fluorescence PCR/ARMS-PCR	7
Søborg	2007	Denmark	Caucasian	PB	PTB	443	432	22	132	289	30	131	271	0.013	PCR-RFLP/PCR-SSP	7

HWE Hardy-Weinberg equilibrium; M Mutated allele; W Wide type allele; HB Hospital-based; PB Population-based; TB Tuberculosis; PTB: Pulmonary TB, EPTB Extra-pulmonary TB; PCR-FLIP Polymerase chain reaction and restrictive fragment length polymorphism; SSP Sequence specific primer; SSOP Sequence-specific oligonucleotide probe; SSCP Single-strand conformation polymorphism; DASH-FRET Dynamic allele-specific hybridization with fluorescence resonance energy transfer; AMLR Allelic-specific multiplex ligase-detection reaction; ARMS Amplification refractory mutation system; NOS Newcastle-Ottawa scale

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ISSN: 1601-5223

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