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Fig. 2 | Hereditas

Fig. 2

From: Identification of MMP1 as a potential gene conferring erlotinib resistance in non-small cell lung cancer based on bioinformatics analyses

Fig. 2

Identification and characterization of DEGs from GSE19188 dataset. a Volcano plot of DEGs between NSCLC tissues and the adjacent normal tissues. Green dots, significantly downregulated DEGs in NSCLC tissues; red dots, significantly upregulated DEGs in NSCLC tissues; black dots, no significant difference (P < 0.01 and |log2FC| ≥ 2 as the threshold cutoff). b The distribution of significant DEGs in NSCLC tissues. The number of the upregulated genes was 122 and the downregulated was 247. The top 5 GO (c) and KEGG pathways (d) of significantly upregulated DEGs were indicated. e Heatmap of top 50 upregulated and downregulated DEGs. Red, upregulation; blue, downregulation. MF, molecular function; CC, cellular component; BP, biological process

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Hereditas

ISSN: 1601-5223

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