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Table 1 The most significant up-regulated and down-regulated genes

From: Identification of potential crucial genes and construction of microRNA-mRNA negative regulatory networks in osteosarcoma

Gene symbol

Log2(FC)

adj.P.Val

up-regulated

 CBS

3.44

4.06E-05

 TMSL8

3.35

0.004377385

 PSAT1

3.20

0.002425845

 PHGDH

3.07

2.24E-06

 ASNS

2.91

0.0002163

 TUBB3

2.73

0.006893245

 MGC39900

2.63

0.003410321

 UBE2C

2.62

0.000193362

 PBK

2.51

9.68E-05

 LARP6

2.48

0.00171183

down-regulated

 HBB

−7.79

5.88E-34

 HBA1

−7.33

2.86E-23

 MMP9

−6.34

1.09E-10

 CD74

−5.84

1.03E-16

 S100A8

−5.83

1.21E-08

 VWF

− 5.64

1.07E-11

 HLA-DRA

−5.54

1.27E-10

 LYZ

−5.43

2.53E-12

 C1QA

−5.28

6.33E-25

 TYROBP

−5.27

1.17E-21