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  1. Mutants have had a fundamental impact upon scientific and applied genetics. They have paved the way for the molecular and genomic era, and most of today’s crop plants are derived from breeding programs involvi...

    Authors: Mats Hansson, Helmy M. Youssef, Shakhira Zakhrabekova, David Stuart, Jan T. Svensson, Christoph Dockter, Nils Stein, Robbie Waugh, Udda Lundqvist and Jerome Franckowiak
    Citation: Hereditas 2024 161:11
  2. The novel form of regulatory cell death, cuproptosis, is characterized by proteotoxicity, which ultimately leads to cell death. Its targeting has emerged as a promising therapeutic approach for oral squamous c...

    Authors: Shuang Liang, Lanting Ji, Zhenyuan Yu, YaHsin Cheng, Ruifang Gao, Wenpeng Yan and Fang Zhang
    Citation: Hereditas 2024 161:10
  3. Oculocutaneous albinism (OCA) is a group of rare genetic disorders characterized by a reduced or complete lack of melanin in the skin, hair, and eyes. Patients present with colorless retina, pale pink iris, an...

    Authors: Yanan Wang, Yujie Chang, Mingya Gao, Weiwei Zang and Xiaofei Liu
    Citation: Hereditas 2024 161:8
  4. Lung adenocarcinoma exhibits high incidence and mortality rates, presenting a significant health concern. Concurrently, the COVID-19 pandemic has emerged as a grave global public health challenge. Existing lit...

    Authors: Jintao Wu, Xiaocheng Mao, Xiaohua Liu, Junying Mao, Xianxin Yang, Xiangwu zhou, Lu Tianzhu, Yulong Ji, Zhao Li and Huijuan Xu
    Citation: Hereditas 2024 161:7
  5. Rheumatoid arthritis (RA) is a chronic inflammatory arthritis. This study aimed to identify potential biomarkers and possible pathogenesis of RA using various bioinformatics analysis tools.

    Authors: Yin Guan, Yue Zhang, Xiaoqian Zhao and Yue Wang
    Citation: Hereditas 2024 161:6
  6. Fibrinogen plays pivotal roles in multiple biological processes. Genetic mutation of the fibrinogen coding genes can result in congenital fibrinogen disorders (CFDs). We identified a novel heterozygous missens...

    Authors: Nuo Xu, Liping Zheng, Zhehao Dai, Jun Zhu, Peng Xie, Shun Yang and Fei Chen
    Citation: Hereditas 2024 161:4
  7. Vascular aging is an important pathophysiological basis for the senescence of various organs and systems in the human body, and it is a common pathogenetic trigger for many chronic diseases in the elderly.

    Authors: Yichao Wen, Haiyang Chen, Yu Wang, Yiqing Sun, Fangfang Dou, Xiling Du, Te Liu and Chuan Chen
    Citation: Hereditas 2024 161:3
  8. Suanzaoren Decoction (SZRD), a well-known formula from traditional Chinese medicine, has been shown to have reasonable cognitive effects while relaxing and alleviating insomnia. Several studies have demonstrat...

    Authors: Tao Chen, Yining Lei, Manqin Li, Xinran Liu, Lu Zhang, Fei Cai, Xiaoming Gong and Ruyi Zhang
    Citation: Hereditas 2024 161:2
  9. As an anticancer Chinese herbal medicine, the effective components and mechanism of Actinidia chinensis Planch (ACP, Tengligen) in the treatment of colon cancer are still unclear. In the present study, the integr...

    Authors: Jin-Fang Chen, Shi-Wei Wu, Zi-Man Shi, Yan-Jie Qu, Min-Rui Ding and Bing Hu
    Citation: Hereditas 2023 160:39
  10. Interstitial lung diseases (ILDs), or diffuse pulmonary lung disease, are a subset of lung diseases that primarily affect lung alveoli and the space around interstitial tissue and bronchioles. It clinically ma...

    Authors: Lv Liu, Hua Luo, Yue Sheng, Xi Kang, Hong Peng, Hong Luo and Liang-Liang Fan
    Citation: Hereditas 2023 160:37
  11. RNA modifications, especially N6-methyladenosine, N1-methyladenosine and 5–methylcytosine, play an important role in the progression of cardiovascular disease. However, its regulatory function in dilated cardi...

    Authors: Wei Yu, Hongli Gao, Tianyang Hu, Xingling Tan, Yiheng Liu, Hongli Liu, Siming He, Zijun Chen, Sheng Guo and Jing Huang
    Citation: Hereditas 2023 160:36
  12. Atrial fibrillation (AF) is the most common type of cardiac arrhythmia. Nonetheless, the accurate diagnosis of this condition continues to pose a challenge when relying on conventional diagnostic techniques. C...

    Authors: Yixin Wang, Qiaozhu Wang, Peng Liu, Lingyan Jin, Xinghua Qin and Qiangsun Zheng
    Citation: Hereditas 2023 160:34
  13. HMGB1 (high mobility group box B-1) exhibits crucial role in tumor genesis and development, including lung cancer. Whereas, more HMGB1-related details in non-small cell lung cancer (NSCLC) are still largely un...

    Authors: Ying Ma, Qin Feng, Bateer Han, Rong Yu and Zhiyong Jin
    Citation: Hereditas 2023 160:33
  14. RNA methylation modifications, such as N1-methyladenosine/N6-methyladenosine /N5-methylcytosine (m1A/m6A/m5C), are the most common RNA modifications and are crucial for a number of biological processes. Nonethele...

    Authors: Hanchao Zhang, Yue Yang, Zhengdao Liu, Hong Xu, Han Zhu, Peirui Wang and Guobiao Liang
    Citation: Hereditas 2023 160:32
  15. Copper-induced cell death (cuproptosis) is a new regulatory cell death mechanism. Long noncoding RNAs (lncRNAs) are related to tumor immunity and metastasis. However, the correlation of cuproptosis-related lnc...

    Authors: Sheng Yu, Lingxue Tang, Qianqian Zhang, Wen Li, Senbang Yao, Yinlian Cai and Huaidong Cheng
    Citation: Hereditas 2023 160:31
  16. Glioma stem cells (GSCs) are responsible for glioma recurrence and drug resistance, yet the mechanisms underlying their maintenance remains unclear. This study aimed to identify enhancer-controlled genes invol...

    Authors: Yu-meng Sun, Yi-meng Zhang, Hai-liang Shi, Song Yang, Yin-long Zhao, Hong-jiang Liu, Chen Li, Hong-lei Liu, Ji-peng Yang, Jian Song, Guo-zhu Sun and Jian-kai Yang
    Citation: Hereditas 2023 160:29
  17. Shattercane [Sorghum bicolor (L.) Moench ssp. Arundinaceum (Desv.)] is a competitive weed in North America's corn, soybean, sorghum, and other agronomic crops. Control of shattercane with POST herbicides in co...

    Authors: Ismail M. Dweikat, Malleswari Gelli, Mark Bernards, Alex Martin and Amit Jhala
    Citation: Hereditas 2023 160:28
  18. Lung cancer is the leading cause of cancer-related deaths worldwide, and despite recent advances in targeted therapies and immunotherapies, the clinical benefit remains limited. Therefore, there is an urgent n...

    Authors: Shan Wei, Jing Xing, Kaining Lu, Kai Wang and Wanjun Yu
    Citation: Hereditas 2023 160:27
  19. Methylmalonic acidemia (MMA) is a rare metabolic disorder resulting from functional defects in methylmalonyl-CoA mutase. Mutations in the MMAB gene are responsible for the cblB type of vitamin B12-responsive MMA.

    Authors: Fereshteh Maryami, Elham Rismani, Elham Davoudi-Dehaghani, Nasrin Khalesi, Fatemeh Zafarghandi Motlagh, Alireza Kordafshari, Saeed Talebi, Hamzeh Rahimi and Sirous Zeinali
    Citation: Hereditas 2023 160:25
  20. Pancreatic cancer (PC) is one of the most common malignant tumors in digestive tract. To explore the role of epigenetic factor EZH2 in the malignant proliferation of PC, so as to provide effective medical help in...

    Authors: Hongfeng Li, Hailong Wang, Yunlong Cui, Wenhua Jiang, Hongjie Zhan, Lixia Feng, Mingyou Gao, Kuo Zhao, Limeng Zhang, Xiaojing Xie, Ning Zhao, Ying Li and Pengfei Liu
    Citation: Hereditas 2023 160:23
  21. Charcot-Marie-Tooth disease(CMT) is a hereditary peripheral neuropathy, characterized by progressive distal hypoesthesia and amyotrophia. CMT is characterized by an X- linked recessive inheritance pattern. The...

    Authors: Chenyu Wang, Zhaojing Lin, ZhuangZhuang Yuan, Tieyu Tang, Liangliang Fan, Yihui Liu and Xuan Wu
    Citation: Hereditas 2023 160:22
  22. The conditions on the mating matrix associated with a stable equilibrium are specified for an autosomal locus with five alleles. This points the way to the maintenance of Hardy-Weinberg proportions with non-ra...

    Authors: Alan E. Stark
    Citation: Hereditas 2023 160:19
  23. Drug-induced hearing loss (DIHL) is very common, and seriously affects people's happiness in life. RG108 is a small molecule inhibitor. RG108 is protective against DIHL. Our purpose is to probe the incidence o...

    Authors: Dongdong Zhang, Yixin Sun, Min Lei, Yue Wang and Chengfu Cai
    Citation: Hereditas 2023 160:18
  24. Dongxiang group, as an important minority, resides in Gansu province which is located at the northwest China, forensic detection system with more loci needed to be studied to improve the application efficiency...

    Authors: Man Chen, Wei Cui, Xiaole Bai, Yating Fang, Hongbin Yao, Xingru Zhang, Fanzhang Lei and Bofeng Zhu
    Citation: Hereditas 2023 160:14
  25. CCNE1 plays an important oncogenic role in several tumors, especially high-stage serous ovarian cancer and endometrial cancer. Nevertheless, the fundamental function of CCNE1 has not been explored in multiple ...

    Authors: Xingyu Zheng, Lingli Chen, Wenlu Liu, Shuangshuang Zhao, Ye Yan, Jianzhen Zhao, Wenyan Tian and Yingmei Wang
    Citation: Hereditas 2023 160:13
  26. Acid sphingomyelinase deficiency (ASMD) disorder, also known as Niemann–Pick disease (NPD) is a rare genetic disease caused by mutations in SMPD1 gene, which encodes sphingomyelin phosphodiesterase (ASM). Except ...

    Authors: Ruisong Wang, Ziyi Qin, Long Huang, Huiling Luo, Han Peng, Xinyu Zhou, Zhixiang Zhao, Mingyao Liu, Pinhong Yang and Tieliu Shi
    Citation: Hereditas 2023 160:11
  27. RNA binding proteins (RBPs) have been implicated in oncogenesis and progression in various cancers. However, the potential value of RBPs as prognostic indicators and therapeutic targets in colorectal cancer (C...

    Authors: Lu Cao, Lili Duan, Rui Zhang, Wanli Yang, Ning Yang, Wenzhe Huang, Xuemin Chen, Nan Wang, Liaoran Niu, Wei Zhou, Junfeng Chen, Yiding Li, Yujie Zhang, Jinqiang Liu, Daiming Fan and Hong Liu
    Citation: Hereditas 2023 160:10
  28. Systemic lupus erythematosus (SLE) is an autoimmune disorder which could lead to inflammation and fibrosis in various organs. Pulmonary fibrosis is a severe complication in patients with SLE. Nonetheless, SLE-...

    Authors: Sheng Liao, Youzhou Tang, Ying Zhang, Qingtai Cao, Linyong Xu and Quan Zhuang
    Citation: Hereditas 2023 160:9
  29. Colonic adenocarcinoma (COAD) is a common gastrointestinal tract tumor, and its occurrence and progression are typically associated with genomic instability, tumor-suppressor gene and oncogene mutations, and t...

    Authors: Hao-lun Wang, Zhuo-miao Ye, Zi-yun He, Lu Huang and Zhi-hui Liu
    Citation: Hereditas 2023 160:6
  30. Functional mutations or polymorphisms affecting forkhead box P3 (FOXP3) can lead to their abnormal FOXP3 gene expression and/or defective Treg cells generation, thus resulting in autoimmune disease and inflammato...

    Authors: Xiaorong Wang, Zejing Liu, Shangdi Zhang, Yinfeng Yang, Xue Wu and Xinyue Liu
    Citation: Hereditas 2023 160:3
  31. Breast cancer is a heterogeneous group of diseases. The polarization of CD4+ T helper (Th) lymphocytes (mainly Th1 and Th2) may differ in breast cancers with different outcomes, but this has not been fully val...

    Authors: Yu Xiao, Yi Huang, Jianping Jiang, Yan Chen and Changyuan Wei
    Citation: Hereditas 2023 160:2
  32. The response of advanced clear cell renal cell carcinoma (ccRCC) to immunotherapy is still not durable, suggesting that the immune landscape of ccRCC still needs to be refined, especially as some molecules tha...

    Authors: Zhi-Cheng Zhang, Yi-Fu Liu, Ping Xi, Ye-Chen Nie, Ting Sun and Bin-Bin Gong
    Citation: Hereditas 2023 160:1

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