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Fig. 8 | Hereditas

Fig. 8

From: Deciphering the potential ability of RG108 in cisplatin-induced HEI-OC1 ototoxicity: a research based on RNA-seq and molecular biology experiment

Fig. 8

In auditory cells (HEI-OC1) cells, BAX was up-regulated and BCL2 was down-regulated after cisplatin injury, but RG108 reversed this phenomenon. A Western blotting was used to detect BCL2, BAX protein levels in HEI-OC1 cells treated with DMSO, CIS, CIS + RG108, RG108. B Use ImageJ to analyze the relative expression of BAX protein. C Use ImageJ to analyze the relative expression of BCL2 protein. Data are expressed as mean ± SD, n = 3,*** P < 0.001, * * * * P < 0.0001, compared with the control group; Compared with cisplatin group, ## P < 0.01, #### P < 0.0001

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