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Fig. 1 | Hereditas

Fig. 1

From: Circular RNA circHMCU promotes breast tumorigenesis through miR-4458/PGK1 regulatory cascade

Fig. 1

Expression and structure of circHMCU in BC. A Expression of circHMCU in Tumor tissues (n = 66) and Normal tumor (n = 66) was measured by qRT-PCR. B The expression of circHMCU in BC cell lines (MDA-MB-231 and MCF-7) and human normal mammary epithelial cell (MCF10A) were determined by qRT-PCR. C Schematic diagram showed the back-splicing was constituted with exon 3 and exon 4 in chr10: 74,474,868–74,475,660. D After RNase R treatment, the expression of circHMCU and linear HMCU were assessed by qRT-PCR. E After Actinomycin D treatment, the levels of circHMCU and linear HMCU were analyzed by qRT-PCR. *P < 0.05

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