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Fig. 6 | Hereditas

Fig. 6

From: m6A-related lncRNA-based immune infiltration characteristic analysis and prognostic model for colonic adenocarcinoma

Fig. 6

Prognostic risk scores correlated with immune score and TNM staging. a Heatmap and clinicopathological features in high- and low-risk groups, except for AL137782.1, AC104819.3, and AC073896.3, which are lncRNAs positively associated with OS, the expression of the other 10 predictors was higher in high-risk group than in the low-risk group. The proportions of cluster subtypes (P < 0.001), TNM stage (P < 0.01), lymph nodes (P < 0.05), and distant metastases (P < 0.01) significantly differed between the high- and low-risk groups. (b-c) Distribution of risk scores stratified by b clusters A–C, c TMN staging, d presence of distant tumor metastases, and e lymph node metastases. Risk scores were significantly higher in cluster B than in clusters A (P < 0.001) and C (b). Patients in TNM stages III and VI had significantly higher risk scores compared to those of patients in stages I and II (c). Risk scores were higher in patients with distant tumor metastases (d) and lymph node metastases (e).  f Association of methylation-related prognostic lncRNAs predictors and risk scores with immune cell infiltration. The bubble map revealed a relationship between the 13 methylation-related prognostic lncRNA predictors and risk scores and the degree of infiltration of 23 immune cells (f). *P < 0.05, **P < 0.01, ***P < 0.001

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