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Table 1 Demographic profile and clinical characteristics of HC, T2DM and T2DN

From: Forkhead box P3 gene polymorphisms predispose to type 2 diabetes and diabetic nephropathy in the Han Chinese populations: a genetic-association and gender-based evaluation study

Characteristics

HC(n = 200)

T2DM(n = 200)

T2DN(n = 200)

t-test

p-value

Males / Females

(%)

48.5/51.5

57.5/42.5

72/28

–

Age (years)

57.57 ± 10.95

61.64 ± 9.80

60.05 ± 10.82

0.135

Disease duration

–

13.16 ± 6.35

13.41 ± 5.78

0.707

Age at Onset of

T2DM (yrs.)

–

48.48 ± 9.53

46.64 ± 9.96

0.069

BMI (Kg/m2)

22.44 ± 0.5

23.85 ± 2.65

24.30 ± 3.32

0.136

Hba1c (%)

–

12.14 ± 3.59

9.23 ± 2.14

0.405

FBS mg/dl

–

10.12 ± 3.77

10.47 ± 4.86

0.416

PLBS mg/dl

–

12.25 ± 4.57

12.67 ± 4.79

0.372

Total cholesterol (mg/dl)

3.81 ± 0.96

4.35 ± 1.14

4.11 ± 1.33

0.064

Triglyceride (mg/dl)

1.29 ± 0.55

1.91 ± 1.24

2.10 ± 2.16

0.285

HDL cholesterol (mg/dl)

1.03 ± 0.26

1.15 ± 0.29

1.07 ± 0.31

0.018

LDL cholesterol (md/dl)

2.57 ± 0.74

2.85 ± 0.87

2.68 ± 0.88

0.047

TC/HDL ratio

3.84 ± 0.96

3.92 ± 1.04

4.01 ± 1.39

0.495

TG/HDL ratio

1.37 ± 0.73

1.88 ± 1.57

2.31 ± 2.95

0.070

Urea(mg/dl)

6.25 ± 2.43

6.79 ± 3.23

9.45 ± 6.63

< 0.001

Creatinine (mg/dl)

57.88 ± 19.04

69.00 ± 55.38

126.88 ± 168.85

< 0.001

Urea/Creatinine ratio

0.11 ± 0.04

0.11 ± 0.03

0.10 ± 0.03

0.010

  1. Test of significance (t-test) was analyzed between T2DM and T2DN. HC Healthy control, T2DM Type 2 Diabetes Mellitus, T2DN Type 2 Diabetic Nephropathy, BMI Body Mass Index, HbA1c Hemoglobin A1c, FBS Fasting Blood Sugar, PLBS Post Lunch Blood Sugar, TC Total Cholesterol, TG Triglycerides, HDL High-Density Lipoproteins, LDL Low-Density Lipoproteins