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Fig. 7 | Hereditas

Fig. 7

From: Upregulation of CENPM is associated with poor clinical outcome and suppression of immune profile in clear cell renal cell carcinoma

Fig. 7

CENPM in relation to immune checkpoint genes, immunotherapy, chemokines and chemokine receptors in ccRCC. (A) CENPM is associated with multiple immune checkpoint genes in human cancers. (B) CENPM was positively correlated with CTLA4, PDCD1, TIGIT and LAG3. (C) Predictions based on the TIDE algorithm suggest that patients with high CENPM expression have a lower response rate to immunotherapy. (D) CENPM was positively correlated with CCL5, CXCL13, CXCR3, CXCR5, etc. ****, p < 0.0001. CENPM, Centromere protein M. ccRCC, clear cell renal cell carcinoma. TIDE, tumor immune dysfunction and exclusion

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Hereditas

ISSN: 1601-5223

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