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Fig. 3 | Hereditas

Fig. 3

From: Bioinformatics analysis of diagnostic biomarkers for Alzheimer's disease in peripheral blood based on sex differences and support vector machine algorithm

Fig. 3

GO and KEGG pathway analyses of DEGs and GSEA plot. A The chord plot of DEGs in females. BP includes GO:1902600, GO:0006119, GO:0042255; CC includes GO:0016469, GO:0071013, GO:0005746; MF includes GO:0015078, GO:0097153, GO:0046961. B The chord plotof DEGs in males. BP includes GO:0031640, GO:0044364, GO:0019730; CC includes GO:0060205, GO:0031983, GO:0034774; MF includes GO:0003735, GO:0019843, GO:0002020. C KEGG in females. D KEGG in males. E GSEA in females. Female-specific pathway includes gap junction (NES = 1.800, p.adj = 0.036), acute myeloid leukemia (NES = 1.693, p.adj = 0.036), chemokine signaling pathway (NES = 1.677, p.adj = 0.040), phosphatidylinositol signaling system (NES = 1.649, p.adj = 0.036), and mapk signaling pathway (NES = 1.608, p.adj = 0.043). F GSEA in males. Male-specific pathway includes toll like receptor signaling pathway (NES = 1.875, p.adj = 0.038) and natural killer cell mediated cytotoxicity (NES = 1.819, p.adj = 0.038)

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Hereditas

ISSN: 1601-5223

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