Table 1 Correlation of CCR5 mRNA expression and clinical prognosis in head and neck squamous cell carcinoma with different clinicopathological factors by Kaplan-Meier plotter
Clinicopathological characteristics | Overall survival (n = 7462) | Recurrence free survival (n = 4420) | ||||
|---|---|---|---|---|---|---|
N | Hazard ratio | p | N | Hazard ratio | p | |
Gender | ||||||
Female | 133 | 0.65 (0.36–1.18) | 0.153 | 46 | 2.03 (0.71–5.85) | 0.1794 |
Male | 366 | 0.5 (0.36–0.69) | 2.4e-5 | 78 | 3.04 (1.06–8.75) | 0.0304 |
Stage | ||||||
1 | 25 | 4.28 (0.44–41.33) | 0.172 | 23 | 8.92 (1.54–51.79) | 0.0041 |
2 | 69 | 0.65 (0.29–1.46) | 0.2945 | 43 | 5.77 (1.06–31.58) | 0.022 |
3 | 78 | 0.32 (0.15–0.68) | 0.002 | 42 | 0.4 (0.11–1.46) | 0.155 |
4 | 259 | 0.67 (0.47–0.96) | 0.0268 | / | / | / |
Race | ||||||
white | 426 | 0.62 (0.46–0.83) | 0.0012 | 110 | 3.97 (1.76–8.89) | 0.0004 |
asian | / | / | / | / | / | / |
black/african america | 47 | 0.51 (0.21–1.24) | 0.131 | / | / | / |
Grade | ||||||
1 | 61 | 0.52 (0.19–1.44) | 0.1991 | 26 | 6.65 (0.78–55.14) | 0.0471 |
2 | 298 | 0.59 (0.42–0.84) | 0.0027 | 69 | 2.37 (0.8–7.01) | 0.1077 |
3 | 119 | 0.59 (0.33–1.07) | 0.0776 | 25 | 5 (0.91–27.57) | 0.0408 |
4 | / | / | / | / | / | / |
Mutation burden | ||||||
high | 251 | 0.58 (0.4–0.83) | 0.0025 | 50 | 5.58 (0.88–14.60 | 0.0592 |
low | 234 | 0.57 (0.35–0.93) | 0.024 | 73 | 3.05 (1.17–7.94) | 0.016 |