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Fig. 3 | Hereditas

Fig. 3

From: Identification of tubulointerstitial genes and ceRNA networks involved in diabetic nephropathy via integrated bioinformatics approaches

Fig. 3

GSEA plot showed the most enriched gene sets in DN. A The most signifcant enriched gene set was extracellar matrix structural constituent (ES = 0.617, NES = 2.414, p < 0.05). B The second signifcant gene set was complement activation (ES = 0.666, NES = 2.386, p < 0.05). C The third signifcant enriched gene set was positive regulation of T cell production (ES = 0.644, NES = 2.364, p < 0.05). D The fourth signifcant enriched gene set was positive rgulation of leukocyte proliferation (ES = 0.612, NES = 2.364, p < 0.05). E The fifth signifcant enriched gene set was antigen processing and presentation (ES = 0.570, NES = 2.325, p < 0.05). F The sixth signifcant enriched gene set was collagen trimer (ES = 0.662, NES = 2.261, p < 0.05). The defined criteria for significant gene sets were |Normalized Enrichment Score (NES)|> 1, False Discovery Rates (FDR) < 0.05 and p-value < 0.05. DN: diabetic nephropathy; ES: enrichment score; NES: normalized enrichment score

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Hereditas

ISSN: 1601-5223

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