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Fig. 7 | Hereditas

Fig. 7

From: ARG1 as a promising biomarker for sepsis diagnosis and prognosis: evidence from WGCNA and PPI network

Fig. 7

ARG1 could play a role in distinguishing sepsis from other similar diseases, predicting the response of treatment, and reflecting the severity of sepsis. A-B ARG1 was upregulated in peripheral blood of patients from Spain (A) and Italy (B) with septic shock compared with non-septic shock. The plots represented the transcript abundance of ARG1, as measured by microarray or RNA-seq. C Dataset from the USA showed the expression level of ARG1 gene in severe sepsis and lethal sepsis was significantly higher than that in uncomplicated sepsis. D Dataset from Germany showed ARG1 was significantly up-regulated in patients with septic shock compared with general sepsis. E Dataset from Italy showed a significant increase of ARG1 expression in non-responders to the early stage of treatment compared with responders

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