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Table 3 Correlation analysis between LPAR2 and relate genes and immune markers in GEPIA

From: LPAR2 correlated with different prognosis and immune cell infiltration in head and neck squamous cell carcinoma and kidney renal clear cell carcinoma

Description

Gene markers

HNSC

KIRC

Tumor

Normal

Tumor

Normal

R

P

R

P

R

P

R

P

CD8 + T cell

CD8A

-0.012

0.79

0.059

0.7

0.26

***

0.027

0.82

CD8B

0.028

0.52

0.06

0.7

0.27

***

-0.17

0.31

T cell(general)

CD3D

0.017

0.7

0.099

0.52

0.33

***

-0.003

0.8

CD3E

0.029

0.51

0.13

0.41

0.32

***

-0.15

0.22

CD2

0.038

0.13

0.4

0.33

0.3

***

-0.12

0.33

B cell

CD19

0.13

0.2

0.19

0.75

0.35

***

-0.15

0.2

CD79A

0.093

*

0.34

*

0.3

***

-0.3

*

Monocyte

CD86

-0.017

0.7

0.23

0.14

0.24

***

-0.06

0.62

CD115(CSF1R)

0.019

0.67

0.22

0.16

0.33

***

-0.072

0.55

TAM

CD68

-0.087

*

0.3

0.051

0.16

***

-0.06

0.62

M1Macrophage

INOS(NOS2)

0.25

***

0.19

0.22

-0.075

0.089

-0.001

0.68

IRF5

0.16

***

0.57

***

0.35

***

-0.049

0.68

M2 Macrophage

VSIG4

-0.027

0.54

0.35

*

0.27

***

0.0054

0.96

Neutrophils

CD11b(ITGAM)

0.15

***

0.22

0.15

0.35

***

-0.16

0.17

CCR7

0.054

0.22

0.14

0.36

0.28

***

-0.034

0.77

Dendritic cell

CD11c(ITGAX)

0.12

**

0.37

*

0.43

***

-0.12

0.33

Th1

STAT4

0.072

0.1

0.26

0.091

0.38

***

- 0.063

0.6

IFN-γ(IFNG)

-0.025

0.56

-0.049

0.75

0.31

***

0.12

0.34

TNF-α(TNF)

0.084

0.055

0.068

0.66

0.28

***

0.27

*

Th2

STAT5A

0.19

***

0.27

0.079

0.36

***

0.17

0.16

Tfh

BCL6

0.26

***

0.4

**

0.33

***

0.78

***

Treg

FOXP3

0.087

*

0.34

*

0.33

***

0.48

***

CCR8

0.06

0.17

0.13

0.39

0.33

***

-0.16

0.17

TGFβ(TGFB1)

0.039

0.38

0.39

**

0.34

***

0.76

***

Tcell exhaustion

PD-1(PDCD1)

0.051

0.25

0.099

0.52

0.4

***

-0.18

0.14

CTLA4

0.086

0.051

0.16

0.31

0.42

***

-0.044

0.72

LAG3

0.039

0.37

0.15

0.32

0.39

***

0.73

***

  1. Cor, R value of Spearman’s correlation; * P < 0.05; ** P < 0.01; *** P < 0.001
  2. Abbreviations: HNSC Head and Neck squamous cell carcinoma, KIRC kidney renal clear cell carcinoma, TAM Tumor-associated macrophages. Tumor, correlation analysis in tumor tissue of TCGA. Normal, correlation analysis in normal tissue of TCGA