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Table 3 Correlation analysis between LPAR2 and relate genes and immune markers in GEPIA

From: LPAR2 correlated with different prognosis and immune cell infiltration in head and neck squamous cell carcinoma and kidney renal clear cell carcinoma

Description Gene markers HNSC KIRC
Tumor Normal Tumor Normal
R P R P R P R P
CD8 + T cell CD8A -0.012 0.79 0.059 0.7 0.26 *** 0.027 0.82
CD8B 0.028 0.52 0.06 0.7 0.27 *** -0.17 0.31
T cell(general) CD3D 0.017 0.7 0.099 0.52 0.33 *** -0.003 0.8
CD3E 0.029 0.51 0.13 0.41 0.32 *** -0.15 0.22
CD2 0.038 0.13 0.4 0.33 0.3 *** -0.12 0.33
B cell CD19 0.13 0.2 0.19 0.75 0.35 *** -0.15 0.2
CD79A 0.093 * 0.34 * 0.3 *** -0.3 *
Monocyte CD86 -0.017 0.7 0.23 0.14 0.24 *** -0.06 0.62
CD115(CSF1R) 0.019 0.67 0.22 0.16 0.33 *** -0.072 0.55
TAM CD68 -0.087 * 0.3 0.051 0.16 *** -0.06 0.62
M1Macrophage INOS(NOS2) 0.25 *** 0.19 0.22 -0.075 0.089 -0.001 0.68
IRF5 0.16 *** 0.57 *** 0.35 *** -0.049 0.68
M2 Macrophage VSIG4 -0.027 0.54 0.35 * 0.27 *** 0.0054 0.96
Neutrophils CD11b(ITGAM) 0.15 *** 0.22 0.15 0.35 *** -0.16 0.17
CCR7 0.054 0.22 0.14 0.36 0.28 *** -0.034 0.77
Dendritic cell CD11c(ITGAX) 0.12 ** 0.37 * 0.43 *** -0.12 0.33
Th1 STAT4 0.072 0.1 0.26 0.091 0.38 *** - 0.063 0.6
IFN-γ(IFNG) -0.025 0.56 -0.049 0.75 0.31 *** 0.12 0.34
TNF-α(TNF) 0.084 0.055 0.068 0.66 0.28 *** 0.27 *
Th2 STAT5A 0.19 *** 0.27 0.079 0.36 *** 0.17 0.16
Tfh BCL6 0.26 *** 0.4 ** 0.33 *** 0.78 ***
Treg FOXP3 0.087 * 0.34 * 0.33 *** 0.48 ***
CCR8 0.06 0.17 0.13 0.39 0.33 *** -0.16 0.17
TGFβ(TGFB1) 0.039 0.38 0.39 ** 0.34 *** 0.76 ***
Tcell exhaustion PD-1(PDCD1) 0.051 0.25 0.099 0.52 0.4 *** -0.18 0.14
CTLA4 0.086 0.051 0.16 0.31 0.42 *** -0.044 0.72
LAG3 0.039 0.37 0.15 0.32 0.39 *** 0.73 ***
  1. Cor, R value of Spearman’s correlation; * P < 0.05; ** P < 0.01; *** P < 0.001
  2. Abbreviations: HNSC Head and Neck squamous cell carcinoma, KIRC kidney renal clear cell carcinoma, TAM Tumor-associated macrophages. Tumor, correlation analysis in tumor tissue of TCGA. Normal, correlation analysis in normal tissue of TCGA