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Table 3 Serum levels of Trp and its metabolites in healthy controls and TB patients (μmol/L)

From: Single-nucleotide polymorphisms and activities of indoleamine 2,3-dioxygenase isoforms, IDO1 and IDO2, in tuberculosis patients

Group n Kyn/Trp Kyn Trp PA QA AA
Healthy controls 60 0.03 ± 0.01 1.70 ± 0.35 52.55 ± 10.45 0.07 ± 0.04 1.95 ± 0.88 0.69 ± 0.03
TB patients 64 0.06 ± 0.03* 2.42 ± 1.02* 48.18 ± 16.56* 0.08 ± 0.05 8.04 ± 10.33* 0.71 ± 0.08
  1. *Significant differences between TB patients and healthy controls, P < 0.05