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Table 3 Serum levels of Trp and its metabolites in healthy controls and TB patients (μmol/L)

From: Single-nucleotide polymorphisms and activities of indoleamine 2,3-dioxygenase isoforms, IDO1 and IDO2, in tuberculosis patients

Group

n

Kyn/Trp

Kyn

Trp

PA

QA

AA

Healthy controls

60

0.03 ± 0.01

1.70 ± 0.35

52.55 ± 10.45

0.07 ± 0.04

1.95 ± 0.88

0.69 ± 0.03

TB patients

64

0.06 ± 0.03*

2.42 ± 1.02*

48.18 ± 16.56*

0.08 ± 0.05

8.04 ± 10.33*

0.71 ± 0.08

  1. *Significant differences between TB patients and healthy controls, P < 0.05