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Table 2 Genotypic and allelic frequencies of IDO2-R248W and IDO2-Y359X in TB patients and healthy controls

From: Single-nucleotide polymorphisms and activities of indoleamine 2,3-dioxygenase isoforms, IDO1 and IDO2, in tuberculosis patients

 

R248W

(n, %)

Y359X

(n, %)

WT (CC)

Heterocigoto (CT)

Homocigoto (TT)

T allele frequency

WT (TT)

Heterocigoto (TA)

Homocigoto (AA)

A allele frequency

Healthy controls (n = 132)

66 (50.0)

51 (38.6)

15 (11.4)

0.31

60 (7.6)

51 (87.1)

21 (5.3)

0.35

Patients (n = 151)

77 (51.0)

65 (43.0)

9 (6.0)

0.28

56 (37.1)

72 (47.7)

23 (15.2)

0.39

Total (n = 283)

143 (12.0)

116 (81.3)

24 (6.7)

0.29

116 (41.0)

123 (43.5)

44 (15.5)

0.37

P-value

0.25

0.40

0.28

0.35