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Table 2 Genotypic and allelic frequencies of IDO2-R248W and IDO2-Y359X in TB patients and healthy controls

From: Single-nucleotide polymorphisms and activities of indoleamine 2,3-dioxygenase isoforms, IDO1 and IDO2, in tuberculosis patients

  R248W
(n, %)
Y359X
(n, %)
WT (CC) Heterocigoto (CT) Homocigoto (TT) T allele frequency WT (TT) Heterocigoto (TA) Homocigoto (AA) A allele frequency
Healthy controls (n = 132) 66 (50.0) 51 (38.6) 15 (11.4) 0.31 60 (7.6) 51 (87.1) 21 (5.3) 0.35
Patients (n = 151) 77 (51.0) 65 (43.0) 9 (6.0) 0.28 56 (37.1) 72 (47.7) 23 (15.2) 0.39
Total (n = 283) 143 (12.0) 116 (81.3) 24 (6.7) 0.29 116 (41.0) 123 (43.5) 44 (15.5) 0.37
P-value 0.25 0.40 0.28 0.35