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Table 2 Summary of the candidate proteins from proteomic profile

From: Multiomics landscape of the autosomal dominant osteopetrosis type II disease-specific induced pluripotent stem cells

Index Protein accession Protein description Fold change Up/ down P value Gene name
1 P22234 Multifunctional protein ADE2 OS=Homo sapiens OX = 9606 GN=PAICS 0.8 Down 0.000035892 PAICS
2 P06727 Apolipoprotein A-IV OS=Homo sapiens OX = 9606 GN = APOA4 0.7 Down 0.035622 APOA4
3 P12268 Inosine-5′-monophosphate dehydrogenase 2 OS=Homo sapiens OX = 9606 GN=IMPDH2 0.814 Down 0.00060007 IMPDH2
4 P40925 “Malate dehydrogenase, cytoplasmic OS=Homo sapiens OX = 9606 GN = MDH1” 0.794 Down 1.2969E-09 MDH1
5 P30566 Adenylosuccinate lyase OS=Homo sapiens OX = 9606 GN = ADSL 0.692 Down 1.7211E-09 ADSL
6 P55209 Nucleosome assembly protein 1-like 1 OS=Homo sapiens OX = 9606 GN=NAP1L1 0.796 Down 0.027664 NAP1L1
7 Q8WUM4 Programmed cell death 6-interacting protein OS=Homo sapiens OX = 9606 GN=PDCD6IP 0.764 Down 0.00058313 PDCD6IP
8 Q96KP4 Cytosolic non-specific dipeptidase OS=Homo sapiens OX = 9606 GN=CNDP2 0.792 Down 1.0982E-06 CNDP2
9 P06744 Glucose-6-phosphate isomerase OS=Homo sapiens OX = 9606 GN = GPI 0.81 Down 3.2818E-08 GPI
10 P00558 Phosphoglycerate kinase 1 OS=Homo sapiens OX = 9606 GN=PGK1 0.798 Down 2.48268E-12 PGK1
11 Q9Y678 Coatomer subunit gamma-1 OS=Homo sapiens OX = 9606 GN=COPG1 1.523 Up 0.00020409 COPG1
12 P02545 Prelamin-A/C OS=Homo sapiens OX = 9606 GN = LMNA 1.3 Up 6.8335E-10 LMNA
13 P00338 L-lactate dehydrogenase A chain OS=Homo sapiens OX = 9606 GN = LDHA 0.73 Down 2.13718E-13 LDHA
14 P18669 Phosphoglycerate mutase 1 OS=Homo sapiens OX = 9606 GN=PGAM1 0.772 Down 3.5611E-06 PGAM1
15 P63167 “Dynein light chain 1, cytoplasmic OS=Homo sapiens OX = 9606 GN=DYNLL1” 0.813 Down 0.0032784 DYNLL1
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Hereditas

ISSN: 1601-5223

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