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Table 5 GO pathway analysis of differentially expressed genes

From: Identification and validation of hub genes of synovial tissue for patients with osteoarthritis and rheumatoid arthritis

Term

ID

Description

Adj.P.Val

Count

OA-specific

BP

GO:0,010,975

regulation of neuron projection development

3.97E-10

92

GO:0,010,769

regulation of cell morphogenesis involved in differentiation

3.97E-10

63

GO:0,045,666

positive regulation of neuron differentiation

6.79E-09

74

CC

GO:0,016,607

nuclear speck

4.51E-10

78

GO:0,090,575

RNA polymerase II transcription factor complex

2.64E-09

37

GO:0,005,912

adherens junction

2.12E-08

87

MF

GO:0,004,674

protein serine/threonine kinase activity

6.24E-10

80

GO:0,000,987

proximal promoter sequence-specific DNA binding

6.24E-10

91

GO:0,000,978

RNA polymerase II proximal promoter sequence-specific DNA binding

3.27E-09

86

RA-specific

BP

GO:0,048,667

cell morphogenesis involved in neuron differentiation

8.82E-10

87

GO:0,010,769

regulation of cell morphogenesis involved in differentiation

1.52E-09

56

GO:0,045,666

positive regulation of neuron differentiation

1.52E-09

68

CC

GO:0,016,607

nuclear speck

1.53E-08

67

GO:0,090,575

RNA polymerase II transcription factor complex

1.17E-06

30

GO:0,005,667

transcription factor complex

1.15E-05

46

MF

GO:0,004,674

protein serine/threonine kinase activity

2.69E-11

75

GO:0,046,332

SMAD binding

4.46E-08

25

GO:0,000,987

proximal promoter sequence-specific DNA binding

2.44E-06

72

  1. GO Gene Ontology, OA osteoarthritis, RA rheumatoid arthritis