Skip to main content

Table 4 Top 5 up- and downregulated DEGs between OA, RA and NC

From: Identification and validation of hub genes of synovial tissue for patients with osteoarthritis and rheumatoid arthritis

Term NC vs. OA   NC vs. RA   OA vs. RA  
  ID Symbol logFC Adj.P.Val ID Symbol logFC Adj.P.Val ID Symbol logFC Adj.P.Val
Up-regulated 4613 MYCN 9.180080878 8.02E-28 8935 SKAP2 9.553082085 1.26E-35 23,094 SIPA1L3 7.79814072 5.46E-25
6598 SMARCB1 9.03478793 8.02E-28 10,745 PHTF1 9.39043259 1.29E-34 1404 HAPLN1 7.87947808 3.69E-22
23,365 ARHGEF12 9.51514144 3.28E-27 22,925 PLA2R1 7.801574317 1.29E-34 5074 PAWR 6.908165575 1.22E-21
5137 PDE1C 9.117030454 4.96E-27 9488 PIGB 9.97554221 1.04E-33 10,100 TSPAN2 5.2303578 4.83E-18
8697 CDC23 9.841678124 6.56E-27 9294 S1PR2 9.470029664 1.04E-33 22,999 RIMS1 4.725490721 6.50E-18
Down-regulated 5340 PLG -5.068734955 2.10E-17 5208 PFKFB2 -7.906263354 5.11E-25 954 ENTPD2 -10.57701223 1.29E-43
7368 UGT8 -7.56536003 7.07E-17 9024 BRSK2 -6.728489168 2.71E-24 4846 NOS3 -9.366652871 3.92E-41
3575 IL7R -6.966596378 3.51E-16 23,308 ICOSLG -7.439436875 8.41E-24 6875 TAF4B -9.588028779 2.08E-40
1404 HAPLN1 -8.500030865 2.05E-15 2676 GFRA3 -7.481477156 2.29E-23 2395 FXN -9.989764717 6.81E-40
22,999 RIMS1 -5.348208851 4.24E-14 6875 TAF4B -8.729849528 2.50E-23 777 CACNA1E -9.95687779 7.39E-39
  1. DEGs differentially expressed genes, OA osteoarthritis, RA rheumatoid arthritis, NC normal control, logFC log fold change