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Table 2 Top 10 up- and downregulated DEGs

From: Identification of crucial genes involved in pathogenesis of regional weakening of the aortic wall

Gene symbol Log FC P-Value Gene official full name
UP-regulated
IGLL5 4.085 0.000788 Immunoglobulin lambda like polypeptide 5
SFRP4 4.048333 0.00244 Secreted frizzled related protein 4
SAA2 3.856667 3.63E-06 Serum amyloid A2
HLA-DRB5 3.7725 0.000798 Major histocompatibility complex, class II, DR beta 5
CD79A 3.7375 0.00175 CD79a molecule
IBSP 3.65 0.019102 Integrin binding sialoprotein
MMP12 3.648333 0.012571 Matrix metallopeptidase 12
CXCL13 3.636667 0.014243 C-X-C motif chemokine ligand 13
DCC 3.555833 0.001552 DCC netrin 1 receptor
FDCSP 3.548333 0.018089 Follicular dendritic cell secreted protein
DOWN-regulated
CNN1 -7.26083 5.03E-09 Calponin 1
ITGA8 -6.8025 3.15E-07 Integrin subunit alpha 8
ACTC1 -6.3375 8.10E-06 Actin, alpha, cardiac muscle 1
MYH11 -6.31667 3.48E-06 Myosin heavy chain 11
MFAP4 -5.71417 1.54E-05 Microfibrillar associated protein 4
PLN -5.65833 3.44E-07 Phospholamban
MYOCD -5.61333 2.76E-07 Myocardin
PPP1R12B -5.51 3.17E-07 Protein phosphatase 1 regulatory subunit 12B
RCAN2 -5.41333 1.96E-09 Regulator of calcineurin 2
PCDH7 -5.405 4.90E-07 Protocadherin 7