Table 2 Ten target genes were involved in the KEGG pathway, including CALM1, AP2M1, NDUFV1, ENO1, PFKM, ATP5B, ATP5C1, GPI, ME3, CDK5R1, which were mainly enriched in Alzheimer's disease, carbon metabolism, glycolysis/gluconeogenesis, and Huntington's disease. The bold label (ENO1, PFKM, ATP5B, ATP5C1, and GPI) meant these genes also belonged to the key hub genes
Symbols | Full Names | Gene IDs |
|---|---|---|
CALM1 | Calmodulin 1 | 801 |
AP2M1 | Adaptor related protein complex 2 subunit mu 1 | 1173 |
NDUFV1 | NADH:ubiquinone oxidoreductase core subunit V1 | 4723 |
ENO1 | Enolase 1 | 2023 |
PFKM | Phosphofructokinase, muscle | 5213 |
ATP5B (ATP5F1B) | ATP synthase F1 subunit beta | 506 |
ATP5C1 (ATP5F1C) | ATP synthase F1 subunit gamma | 509 |
GPI | Glucose-6-phosphate isomerase | 2821 |
ME3 | Malic enzyme 3 | 10,873 |
CDK5R1 | Cyclin dependent kinase 5 regulatory subunit 1 | 8851 |