Fig. 6

Phenotype analysis of Axin2 homozygous (Axin2^−/−) and heterozygous (Axin2^+/−) knockout mice. Data of Axin2^−/− and Axin2^+/− mice were obtained from IMPC. a Axin2^−/− mice could not be alive due to preweaning lethality. Number and percentage of Axin2^+/− and matched Axin2^+/+ mice at early adult stage. b Number and percentage of female mice (Axin2^+/+, Axin2^−/−) with abnormal craniofacial morphology at E12.5. c Number and percentage of mice (Axin2^+/+, Axin2^+/−, Axin2^−/−) with abnormal head shape at E18.5