Skip to main content
Fig. 4 | Hereditas

Fig. 4

From: An Axin2 mutation and perinatal risk factors contribute to sagittal craniosynostosis: evidence from a Chinese female monochorionic diamniotic twin family

Fig. 4

Conservation analysis of Axin2 (c.1181G > A, p.R394H, rs200899695). a Schematic diagram depicts structure of AXIN2 protein. The mutation (R to H at 394th amino acid) resides in AXIN2 GSK3β binding domain. (TNKS_binding: Tankyrase binding N-terminal segment of AXIN; RGS: Regulator of G protein signaling; DIX: Disheveled and AXIN interacting) (b) Evolutionary conservation analysis revealed that the Arg394 site is conserved from zebrafish to humans. c WebLogo analysis showed that the Arg394 site was relatively conserved

Back to article page

Hereditas

ISSN: 1601-5223

Contact us