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Fig. 3 | Hereditas

Fig. 3

From: An Axin2 mutation and perinatal risk factors contribute to sagittal craniosynostosis: evidence from a Chinese female monochorionic diamniotic twin family

Fig. 3

Sequence analysis of Axin2 (c.1181G > A, p.R394H, rs200899695). a-e Integrative Genomics Viewer (IGV) of the sequences around Axin2 (c.1181G > A, p.R394H, rs200899695) and the results of Sanger sequencing were shown. The gDNA samples were extracted from peripheral leucocytes of the parents and twin sisters (a-d) and from skull periosteum tissue of the proband (e). Please note that the DNA sequences are shown in + strand, but Axin2 is located on-strand. The father and two twins have this missense mutation (a, c, d, e), but the mother does not carry this mutation (b)

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Hereditas

ISSN: 1601-5223

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