Genetic polymorphism of IDOL gene was associated with the susceptibility of coronary artery disease in Han population in Xinjiang, China

Table 1 Baseline characteristics of study population

Groups	Age, years	Male, n (%)	Smoking, n (%)	Drinking, n (%)	Hypertension, n (%)	Diabetes, n (%)	TG, mmol/L	TC, mmol/L	HDL-C, mmol/L	LDL-C, mmol/L	FPG, mmol/L	hs-CRP, mg/L	CK, IU/L	ApoA, g/L	ApoB, g/L
Han
CAD group	61.26 ± 10.99	333 (74.3%)	224 (50.0%)	243 (54.2%)	257 (57.4%)	116 (25.9%)	2.03 ± 1.45	4.86 ± 0.86	1.00 ± 0.33	3.05 ± 1.34	6.33 ± 2.63	2.02 ± 0.72	91.52 ± 8.08	1.24 ± 0.31	0.83 ± 0.40
Control group	56.11 ± 12.86	165 (48.1%)	116 (33.8%)	95 (27.7%)	140 (40.8%)	41 (12.0%)	1.87 ± 1.54	4.15 ± 1.11	1.26 ± 0.58	2.53 ± 0.96	5.70 ± 2.00	1.99 ± 0.67	90.87 ± 10.64	1.22 ± 0.49	0.81 ± 0.24
χ² or t	6.067	57.292	20.753	55.934	21.284	23.728	1.487	9.901	8.068	6.346	3.736	0.521	0.961	0.702	0.881
P value	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001	0.137	< 0.001	< 0.001	< 0.001	< 0.001	0.602	0.337	0.483	0.379
Uygur
CAD group	56.07 ± 9.57	247 (81.3%)	129 (42.4%)	137 (45.1%)	177 (58.2%)	70 (23.0%)	1.97 ± 1.15	4.49 ± 1.11	0.91 ± 0.60	2.92 ± 1.43	6.16 ± 2.53	2.21 ± 0.71	89.97 ± 6.82	1.14 ± 0.25	0.83 ± 0.25
Control group	52.67 ± 8.61	139 (43.7%)	66 (20.8%)	28 (8.8%)	148 (46.5%)	28 (8.8%)	1.63 ± 1.07	4.21 ± 1.38	1.21 ± 0.47	2.65 ± 1.32	5.12 ± 2.74	2.10 ± 0.63	88.72 ± 9.25	1.12 ± 0.29	0.80 ± 0.26
χ² or t	4.719	93.017	33.941	104.849	8.502	23.682	3.706	2.758	6.968	2.377	6.021	2.169	1.893	1.35	0.29
P value	< 0.001	< 0.001	< 0.001	< 0.001	0.004	< 0.001	< 0.001	0.006	< 0.001	0.018	< 0.001	0.03	0.059	0.178	0.197

Data are presented as Number of patients (%) or mean standard ± deviation
Note: For both Han and Uygur groups, the mean age of patients with CAD was higher than control group’. The prevalence of smoking, diabetes, hypertension, and drinking was higher in case group. LDL-C, TC, FPG levels were higher in case group. HDL-C levels were lower in case group. The TG and hs-CRP levels were higher in Uygur CAD patients
TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, FPG fasting plasma glucose, hs-CRP high sensitive C reactive protein, CK creatine kinase, ApoA Apolipoprotein A, ApoB Apolipoprotein B

ISSN: 1601-5223