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Table 2 Associations between urate-related epistatic interactions and hyperuricemia/gout

From: Epistatic interaction between PKD2 and ABCG2 influences the pathogenesis of hyperuricemia and gout

SNP1

SNP2

 

Hyperuricemia Vs. Control

Gout Vs. Hyperuricemia

Gout Vs. Control

Estimate

SE

Pint

Estimate

SE

Pint

Estimate

SE

Pint

rs2728121

rs1481012

Male

−0.108

0.153

0.483

0.188

0.245

0.444

0.077

0.258

0.765

Female

−0.648

0.272

0.017

−0.528

0.947

0.577

−0.897

0.835

0.282

Total

−0.254

0.130

0.051

0.165

0.234

0.482

−0.004

0.239

0.987

rs2728121

rs2231137

Male

0.206

0.087

0.018

0.338

0.156

0.030

0.524

0.161

0.001

Female

0.118

0.148

0.427

0.100

0.536

0.852

0.229

0.523

0.661

Total

0.193

0.074

0.009

0.313

0.149

0.035

0.480

0.149

0.001

  1. SNP1 (SNP2), name of the first (second) SNP. SE, standard error. Pint, P-value of the interaction between the SNP pair in hyperuricemia and gout were calculated by logistic regression adjusted age, gender, and target SNPs