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Table 2 Associations between urate-related epistatic interactions and hyperuricemia/gout

From: Epistatic interaction between PKD2 and ABCG2 influences the pathogenesis of hyperuricemia and gout

SNP1SNP2 Hyperuricemia Vs. ControlGout Vs. HyperuricemiaGout Vs. Control
EstimateSEPintEstimateSEPintEstimateSEPint
rs2728121rs1481012Male−0.1080.1530.4830.1880.2450.4440.0770.2580.765
Female−0.6480.2720.017−0.5280.9470.577−0.8970.8350.282
Total−0.2540.1300.0510.1650.2340.482−0.0040.2390.987
rs2728121rs2231137Male0.2060.0870.0180.3380.1560.0300.5240.1610.001
Female0.1180.1480.4270.1000.5360.8520.2290.5230.661
Total0.1930.0740.0090.3130.1490.0350.4800.1490.001
  1. SNP1 (SNP2), name of the first (second) SNP. SE, standard error. Pint, P-value of the interaction between the SNP pair in hyperuricemia and gout were calculated by logistic regression adjusted age, gender, and target SNPs