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Table 2 GO analysis of up-regulated and down-regulated DEGs

From: Identification of differentially expressed genes, signaling pathways and immune infiltration in rheumatoid arthritis by integrated bioinformatics analysis

ID

Description

Adjusted P-values

Gene symbol

Count

Up-regulated

GO:0004896

cytokine receptor activity

8.17E-09

IL21R/IL7R/IL2RG/CCR5/CCR2/CSF2RB/CCR7/CXCR4/CXCR6/CXCR3/CD4/CCR1/IL2RA/IL15RA/CX3CR1/CD74/CCRL2/IL1RL1/CXCR5/CCR6

20

GO:0001637

G protein-coupled chemoattractant receptor activity

1.30E-07

CCR5/CCR2/CCR7/CXCR4/CXCR6/CXCR3/CCR1/CX3CR1/CCRL2/CXCR5/CCR6

11

GO:0004950

chemokine receptor activity

1.30E-07

CCR5/CCR2/CCR7/CXCR4/CXCR6/CXCR3/CCR1/CX3CR1/CCRL2/CXCR5/CCR6

11

GO:0023023

MHC protein complex binding

1.30E-07

HLA-DOB/MS4A1/CD8A/HLA-DMB/HLA-DMA/KLRD1/LILRB2/LILRB1/HLA-DRA/TAPBPL/CD74

11

GO:0019956

chemokine binding

7.20E-07

ITGA4/CCR5/CCR2/CCR7/CXCR4/CXCR6/CXCR3/CCR1/CX3CR1/CCR6

10

Down-regulated

GO:0004601

peroxidase activity

0.044092206

DUOX2/GPX3/PTGS2

3

GO:0016684

oxidoreductase activity, acting on peroxide as acceptor

0.044092206

DUOX2/GPX3/PTGS2

3

  1. GO gene ontology, DEGs differentially expressed genes