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Table 2 Comparison of RELN expression levels in controls, and SCZ patients before and after treatment (2−ΔΔCt)

From: Exploring the mRNA expression level of RELN in peripheral blood of schizophrenia patients before and after antipsychotic treatment

 

RELN

P

Total

Control (48)

1.25 ± 0.13

 

SCZ (30)

0.86 ± 0.09

0.0476 a

SCZ_12W (30)

1.32 ± 0.15

0.0384 b

Female

Control (31)

1.20 ± 0.14

 

SCZ (16)

0.64 ± 0.07

0.0025 a

SCZ_12W (16)

1.33 ± 0.24

0.0507 b

Male

Control (17)

1.35 ± 0.28

 

SCZ (14)

1.10 ± 0.16

0.9844 a

SCZ_12W (14)

1.32 ± 0.17

0.3575 b

  1. Abbreviations: Control Healthy control, SCZ Untreated schizophrenia patients, SCZ_12w Schizophrenia patients after 12 weeks of antipsychotic treatment; a: comparisons between the untreated schizophrenia patients and healthy control (Mann-Whitney U test); b: comparisons between the schizophrenia patients after 12 weeks of antipsychotic treatment and untreated schizophrenia patients (paired Wilcoxon signed-rank test); Bold figures indicate P < 0.05