Table 2 Association analysis of SNPs in different genetic models (age and sex adjusted) between cases and controls with Bonferroni corrected p -values

rs358592 (Risk = C)

(KCNIP4)

0.268

0.343

5.174

(0.165–0.434)

(p < 2.50E^− 08)

(0.143–0.823)

(p = 0.425)

(2.094–12.788)

(p < 2.50E^− 08)

Heterozygous

rs1109089 (Risk = T)

(RHEB)

3.477

2.047

0.268

(2.137–5.656)

(p < 2.50E^− 08)

(1.101–3.805)

(p = 0.575)

(0.136–0.531)

(p < 2.50E^− 08)

Heterozygous

rs10448044 (Risk = C)

(IL7)

2.091

3.314

0.306

(1.27–3.442)

(p = 0.1)

(1.993–5.509)

(p < 2.50E⁻⁰⁸)

(0.175–0.535)

(p < 2.50E^− 08)

Heterozygous

–

–

–

0.293

(0.15–0.575)

(p < 2.50E⁻⁰⁸)

Homozygous

rs4732812 (Risk = T)

(NUGCC)

8.122

1.457

0.201

(4.002–16.483)

(p < 2.50E⁻⁰⁸)

(0.639–3.32)

(p = 1)

(0.076–0.531)

(p = 0.025)

Heterozygous

rs10448042 (Risk = G)

(IL7)

1.205

5.097

0.273

(0.666–2.179)

(p = 1)

(2.53–10.27)

(p < 2.50E⁻⁰⁸)

(0.13–0.572)

(p = 0.025)

Heterozygous

–

–

–

0.097

(0.038–0.251)

(p < 2.50E⁻⁰⁸)

Homozygous

rs10997044 (Risk = A)

(CTNNA3)

12.363

36.591

0.026

(5.236–29.192)

(p < 2.50E⁻⁰⁸)

(9.92–134.974)

(p < 2.50E^− 08)

(0.007–0.096)

(p < 2.50E^− 08)

Heterozygous

–

–

–

0.052

(0.009–0.301)

(p = 0.025)

Homozygous

rs203136 (Risk = G)

(ARFGEF3)

0.331

0.944

2.416

(0.152–0.719)

(p = 0.005)

(0.498–1.787)

(p = 0.859)

(1.068–5.462)

(p = 0.034)

Heterozygous