Fig. 3
From: miR-183-3p suppresses proliferation and migration of keratinocyte in psoriasis by inhibiting GAB1
MiR-183-3p negatively regulated GAB1 expression in keratinocytes. a Putative binding sites between GAB1 and miR-183-3p. b MiR-183-3p decreased the luciferase activity of pmirGLO-wt-GAB1 compared to pmirGLO-mut-GAB1 in HaCaT cells. *** represents miR-183-3p mimics vs. NC mimic, p < 0.001. c MiR-183-3p decreased mRNA expression of GAB1 in HaCaT cells, while miR-183-3p inhibitor increased GAB1 expression. ** represents miR-183-3p mimics vs. NC mimic, p < 0.01. ### represents miR-183-3p inhibitor vs. NC inhibitor, p < 0.001. d MiR-183-3p decreased protein expression of GAB1 in HaCaT cells, while miR-183-3p inhibitor increased GAB1 expression. ** represents miR-183-3p mimics vs. NC mimic, p < 0.01. ## represents miR-183-3p inhibitor vs. NC inhibitor, p < 0.01