Skip to main content

Table 1 Study characteristics of all included studies about urinary cancer

From: Association between methylenetetrahydrofolate reductase gene rs1801131 A/C polymorphism and urinary tumors’ susceptibility

First authorYearOriginEthnicityDesignSource of controlCaseControlCaseControlHWE in controlGenotype methodNOS
CCCAAACCCAAA
Bladder cancer
 Ouerhani2007TunisiaAfricanHB 11113164758937850.55PCR-RFLP6
 Rouissi2009TunisiaAfricanHB 18519110789710601210.478PCR-RFLP7
 Cai2009ChinaAsianHB 3123256912157922260.504PCR-RFLP7
 Izmirli2011TurkeyCaucasianHB 475032519729140.195PCR-RFLP6
 Safarinejad2011IranCaucasianHB 158316258548231151780.46PCR-RFLP8
 Lin2004USAAfricanPB 2121071408130.281PCR-RFLP9
 Wang2009ChinaAsianPB 2392503671694751710.719PCR-RFLP9
 Beebe-Dimmer2012USACaucasianPB 2182721410995341111270.211Taqman8
 Karagas2005USACaucasianPB 35054231146173552202670.333PCR-RFLP9
 Lin2004USACaucasianPB 41040930188192361841890.35PCR-RFLP9
 Moore2007SpainCaucasianPB 1068107874457537924295570.467TaqMan7
 Sanyal2004GermanyCaucasianPB 31124533133145241111100.6PCR-RFLP7
 Lin2004USAMixedPB 1717041315110.678PCR-RFLP9
 Moore2004USAMixedPB 10610894552845550.771TaqMan8
Prostate cancer
 Cicek2004USAMixedPBHealthy43947839205195442012330.945PCR-RFLP8
 Collin2009UKCaucasianPBHealthy15923035144673775289133914070.249PCR-RFLP9
 Cai2010ChinaAsianHBBPH2172204631505711440.27PCR-RFLP6
 Safarinejad2010IranCaucasianHBHealthy174348147090401501580.628PCR-RFLP7
 Singal2004USACaucasianHBBPH814294329717180.396PCR-RFLP8
 Wu2010TaiwanAsianHBHealthy2184361070138141352870.697PCR-RFLP7
 Marchal2008SpainCaucasianHBHealthy17720917629822791080.193TaqMan7
 Stevens2008USACaucasianPBHealthy110411091055184811254934910.94TaqMan7
 Guelpen2006SwedenCaucasianPBHealthy2224342710887552031760.765TaqMan7
 Muslumanoglu2009TurkeyCaucasianHBBPH91166441631444577< 0.05PCR-RFLP6
 López-Cortés2013USACaucasianPBHealthy1041102210011108< 0.05PCR-RFLP9
Renal cell carcinoma
 Ajaz2012PakistanAsianHB 1681721910643810559< 0.05PCR-RFLP6
 Safarinejad2012IranCaucasianPB 152304288836351311380.645PCR-RFLP9
 Moore2008FranceCaucasianHB 8181087853573761134834910.718PCR-RFLP7
  1. HB hospital-based, PB population-based, PCR-RFLP polymerase chain reaction and restrictive fragment length polymorphism, HWE Hardy–Weinberg equilibrium, NOS Newcastle-Ottawa Score