Association between methylenetetrahydrofolate reductase gene rs1801131 A/C polymorphism and urinary tumors’ susceptibility

Xu, Shuaili; Zuo, Li

doi:10.1186/s41065-020-00129-x

Table 1 Study characteristics of all included studies about urinary cancer

From: Association between methylenetetrahydrofolate reductase gene rs1801131 A/C polymorphism and urinary tumors’ susceptibility

First author	Year	Origin	Ethnicity	Design	Source of control	Case	Control	Case			Control			HWE in control	Genotype method	NOS
First author	Year	Origin	Ethnicity	Design	Source of control	Case	Control	CC	CA	AA	CC	CA	AA	HWE in control	Genotype method	NOS
Bladder cancer
Ouerhani	2007	Tunisia	African	HB		111	131	6	47	58	9	37	85	0.55	PCR-RFLP	6
Rouissi	2009	Tunisia	African	HB		185	191	10	78	97	10	60	121	0.478	PCR-RFLP	7
Cai	2009	China	Asian	HB		312	325	6	91	215	7	92	226	0.504	PCR-RFLP	7
Izmirli	2011	Turkey	Caucasian	HB		47	50	3	25	19	7	29	14	0.195	PCR-RFLP	6
Safarinejad	2011	Iran	Caucasian	HB		158	316	25	85	48	23	115	178	0.46	PCR-RFLP	8
Lin	2004	USA	African	PB		21	21	0	7	14	0	8	13	0.281	PCR-RFLP	9
Wang	2009	China	Asian	PB		239	250	3	67	169	4	75	171	0.719	PCR-RFLP	9
Beebe-Dimmer	2012	USA	Caucasian	PB		218	272	14	109	95	34	111	127	0.211	Taqman	8
Karagas	2005	USA	Caucasian	PB		350	542	31	146	173	55	220	267	0.333	PCR-RFLP	9
Lin	2004	USA	Caucasian	PB		410	409	30	188	192	36	184	189	0.35	PCR-RFLP	9
Moore	2007	Spain	Caucasian	PB		1068	1078	74	457	537	92	429	557	0.467	TaqMan	7
Sanyal	2004	Germany	Caucasian	PB		311	245	33	133	145	24	111	110	0.6	PCR-RFLP	7
Lin	2004	USA	Mixed	PB		17	17	0	4	13	1	5	11	0.678	PCR-RFLP	9
Moore	2004	USA	Mixed	PB		106	108	9	45	52	8	45	55	0.771	TaqMan	8
Prostate cancer
Cicek	2004	USA	Mixed	PB	Healthy	439	478	39	205	195	44	201	233	0.945	PCR-RFLP	8
Collin	2009	UK	Caucasian	PB	Healthy	1592	3035	144	673	775	289	1339	1407	0.249	PCR-RFLP	9
Cai	2010	China	Asian	HB	BPH	217	220	4	63	150	5	71	144	0.27	PCR-RFLP	6
Safarinejad	2010	Iran	Caucasian	HB	Healthy	174	348	14	70	90	40	150	158	0.628	PCR-RFLP	7
Singal	2004	USA	Caucasian	HB	BPH	81	42	9	43	29	7	17	18	0.396	PCR-RFLP	8
Wu	2010	Taiwan	Asian	HB	Healthy	218	436	10	70	138	14	135	287	0.697	PCR-RFLP	7
Marchal	2008	Spain	Caucasian	HB	Healthy	177	209	17	62	98	22	79	108	0.193	TaqMan	7
Stevens	2008	USA	Caucasian	PB	Healthy	1104	1109	105	518	481	125	493	491	0.94	TaqMan	7
Guelpen	2006	Sweden	Caucasian	PB	Healthy	222	434	27	108	87	55	203	176	0.765	TaqMan	7
Muslumanoglu	2009	Turkey	Caucasian	HB	BPH	91	166	44	16	31	44	45	77	< 0.05	PCR-RFLP	6
López-Cortés	2013	USA	Caucasian	PB	Healthy	104	110	2	2	100	1	1	108	< 0.05	PCR-RFLP	9
Renal cell carcinoma
Ajaz	2012	Pakistan	Asian	HB		168	172	19	106	43	8	105	59	< 0.05	PCR-RFLP	6
Safarinejad	2012	Iran	Caucasian	PB		152	304	28	88	36	35	131	138	0.645	PCR-RFLP	9
Moore	2008	France	Caucasian	HB		818	1087	85	357	376	113	483	491	0.718	PCR-RFLP	7

HB hospital-based, PB population-based, PCR-RFLP polymerase chain reaction and restrictive fragment length polymorphism, HWE Hardy–Weinberg equilibrium, NOS Newcastle-Ottawa Score

Back to article page

ISSN: 1601-5223

Contact us

Submission enquiries: Access here and click Contact Us
General enquiries: info@biomedcentral.com

Hereditas

Contact us