TY - JOUR AU - Xu, Shuaili AU - Zuo, Li PY - 2020 DA - 2020/04/27 TI - Association between methylenetetrahydrofolate reductase gene rs1801131 A/C polymorphism and urinary tumors’ susceptibility JO - Hereditas SP - 16 VL - 157 IS - 1 AB - The methylenetetrahydrofolate reductase (MTHFR) rs1801131 A/C variant results in a decrease in MTHFR enzymatic activity, which may play an important role in folate metabolism and is also an important source of DNA methylation and DNA synthesis. Several case-control studies have been conducted to assess the association of MTHFR rs1801131 polymorphism with the risk of urinary cancers, yet with conflicting conclusions. To derive a more precise estimation of above relationship, the association between the MTHFR rs1801131 A/C polymorphism and the risk of urinary cancer was performed. SN - 1601-5223 UR - https://doi.org/10.1186/s41065-020-00129-x DO - 10.1186/s41065-020-00129-x ID - Xu2020 ER -